產品名稱
Anti-Choline acetyltransferase antibody produced in goat, affinity isolated antibody, buffered aqueous solution
生物源
goat
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
canine, chimpanzee, human, pig
技術
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CHAT(1103)
1 of 4
本產品 | AMAB91130 | SAB2108655 | AMAB91129 |
|---|---|---|---|
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| antibody form affinity isolated antibody | antibody form purified immunoglobulin | antibody form affinity isolated antibody | antibody form purified immunoglobulin |
| biological source goat | biological source mouse | biological source rabbit | biological source mouse |
| species reactivity canine, chimpanzee, human, pig | species reactivity mouse, human, rat | species reactivity dog, human, horse | species reactivity mouse, rat, human |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
一般說明
Choline acetyltransferase (CHAT) has a molecular weight of about 68kDa. It is synthesized in the parakaryon and is transported to the axon terminals. CHAT is part of the choline/carnitine acyltransferase family.
免疫原
Peptide with sequence CKEKATRPSQGHQP from the C Terminus of the protein sequence according to NP_065574; NP_066264; NP_066265; NP_066266.
生化／生理作用
Choline acetyltransferase (CHAT) is involved in the synthesis of acetylcholine in neurons. It catalyzes the transfer of an acetyl group between acetyl-coenzyme A and choline. Mutations in the gene encoding this protein have been associated with congenital neuromuscular disorders.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase.
Olofsson PS, e.al
Nature Biotechnology (2016)
Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders
The Embo Journal (2004)
Francesco Antoniani et al.
Cell death discovery, 9(1), 248-248 (2023-07-16)
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are two neurodegenerative disorders that share genetic causes and pathogenic mechanisms. The critical genetic players of ALS and FTD are the TARDBP, FUS and C9orf72 genes, whose protein products, TDP-43, FUS and
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