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Merck

WH0009340M5

Monoclonal Anti-GLP2R antibody produced in mouse

clone 1F2, purified immunoglobulin, buffered aqueous solution

同義詞:

Anti-glucagon-like peptide 2 receptor

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分類程式碼代碼:
12352203
NACRES:
NA.41

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生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1F2, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

indirect ELISA: suitable
western blot: 1-5 μg/mL

同型

IgG2bκ

GenBank登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... GLP2R(9340)

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1 of 4

本產品
WH0002641M1SAB4501220WH0001269M1
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... GLP2R(9340)

Gene Information

human ... GCG(2641)

Gene Information

human ... GLP1R(2740)

Gene Information

human ... CNR2(1269)

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

mouse

clone

1F2, monoclonal

clone

2D3-2B11, monoclonal

clone

polyclonal

clone

3C7, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human, mouse

species reactivity

human

一般說明

The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). (provided by RefSeq)

免疫原

GLP2R (NP_004237, 69 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTL

外觀

Solution in phosphate buffered saline, pH 7.4

法律資訊

GenBank is a registered trademark of United States Department of Health and Human Services

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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