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Effects of carnosine and related compounds on the stability and morphology of erythrocytes from alcoholics.

Alcohol and alcoholism (Oxford, Oxfordshire) (2000-02-24)
V D Prokopieva, N A Bohan, P Johnson, H Abe, A A Boldyrev
ABSTRACT

The effects of carnosine and related compounds on erythrocytes from alcoholics were studied. In their presence, erythrocytes showed an increased ability to resist haemolysis and showed a more normal morphology, with carnosine and N-acetyl-carnosine being the most effective compounds. These beneficial properties of the dipeptides do not appear to be directly related to their antioxidant or buffering properties.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
PIPES, ≥99% (titration)
Sigma-Aldrich
PIPES, BioPerformance Certified, suitable for cell culture
Sigma-Aldrich
PIPES, BioXtra, for molecular biology, ≥99.5% (T)
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PIPES, BioXtra, ≥99% (titration)
Sigma-Aldrich
PIPES sodium salt, ≥99% (titration)

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