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Gemfibrozil-induced myopathy.

Archives of internal medicine (1991-09-01)
G J Magarian, L M Lucas, C Colley
ABSTRACT

Drug-induced myopathy has been reported with use of lovastatin, nicotinic acid, and clofibrate. A particularly severe form, often accompanied by rhabdomyolysis, has been reported with the use of lovastatin and gemfibrozil; however, as far as we know, no case has been documented with use of gemfibrozil alone. Herein, we report the first case (to our knowledge of gemfibrozil-induced myopathy, confirmed by drug rechallenge.

MATERIALS
Product Number
Brand
Product Description

Gemfibrozil for system suitability, European Pharmacopoeia (EP) Reference Standard
Gemfibrozil, European Pharmacopoeia (EP) Reference Standard
Supelco
Gemfibrozil, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Gemfibrozil