24880

5-Chloro-7-iodo-8-quinolinol

≥95.0% (HPLC)

• Synonym(s): 5-Chloro-8-hydroxy-7-iodoquinoline, Clioquinol, Iodochlorhydroxyquin
• Empirical Formula (Hill Notation): C₉H₅ClINO
• CAS Number: 130-26-7
• Molecular Weight: 305.50
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 57648095
• EC Number: 204-984-4
• Beilstein/REAXYS Number: 153637
• MDL number: MFCD00006787
• Assay: ≥95.0% (HPLC)
• Form: powder

Properties

• Quality Segment: 200
• assay: ≥95.0% (HPLC)
• form: powder
• solubility: dioxane: soluble 0.5 g/10 mL, clear, faintly yellow to yellow
• functional group: chloro, iodo
• SMILES string: Oc1c(I)cc(Cl)c2cccnc12
• InChI: 1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
• InChI key: QCDFBFJGMNKBDO-UHFFFAOYSA-N

Description

General description

5-Chloro-7-iodo-8-quinolinol is an antibiotic with metal-binding properties and exhibits anticancer activity in vitro and in vivo. 5-Chloro-7-iodo-8-quinolinol, its glucuronide and sulfate in serum, urine and milk has been quantitated by gas chromatography.

Application

5-Chloro-7-iodo-8-quinolinol has been used in analysis of intracellular free zinc ions with the FluoZin-3 probes using fluorescence microscopy.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H301,H315,H317,H319
• Precautionary Statements: P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• PPE (personal protective equipment): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges