382272

Chelidonic acid

≥95%

• Synonym(s): 4-Oxo-4H-pyran-2,6-dicarboxylic acid
• Empirical Formula (Hill Notation): C₇H₄O₆
• CAS Number: 99-32-1
• Molecular Weight: 184.10
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24863888
• EC Number: 202-749-0
• Beilstein/REAXYS Number: 163607
• MDL number: MFCD00006577
• Assay: ≥95%
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥95%
• form: powder
• mp: 265 °C (dec.) (lit.)
• functional group: carboxylic acid, ether, ketone
• SMILES string: OC(=O)C1=CC(=O)C=C(O1)C(O)=O
• InChI: 1S/C7H4O6/c8-3-1-4(6(9)10)13-5(2-3)7(11)12/h1-2H,(H,9,10)(H,11,12)
• InChI key: PBAYDYUZOSNJGU-UHFFFAOYSA-N

Description

General description

Chelidonic acid (CA) is a γ-pyrone. It is reported as constituent of the rhizome of Chelidonium majus L. It has many pharmacological effects, such as mild analgesic and antimicrobial effects. Therapeutic potential of CA for the treatment of intestinal inflammation has been investigated. CA is reported as inhibitor of the rat brain glutamate decarboxylase. Biosynthesis of CA in cell suspension cultures of Leucojum aestivum has been studied.

Application

Chelidonic acid is suitable for use a in homogeneous preparation of native dihydrodipicolinate synthase from pea. It may be used as endocyclic oxygen-containing ligand in the synthesis of aqua[bis(2-pyridylmethyl)amine][chelidonato(1.5-)]-copper(II) chelidonate(0.5-) monohydrate.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves