419656

N-Benzyl-2-nitro-1H-imidazole-1-acetamide

97%

• Synonym(s): 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide, Benzonidazol, N-Benzyl-2-nitroimidazol-1-yl-acetamide
• Empirical Formula (Hill Notation): C₁₂H₁₂N₄O₃
• CAS Number: 22994-85-0
• Molecular Weight: 260.25
• NACRES: NA.22
• PubChem Substance ID: 24866267
• UNSPSC Code: 12352100
• MDL number: MFCD00243089
• Assay: 97%

Properties

• Quality Segment: 100
• assay: 97%
• mp: 189-192 °C (lit.)
• solubility: methanol: soluble 50 mg/mL, clear, colorless to yellow
• functional group: amide, nitro, phenyl
• SMILES string: [O-][N+](=O)c1nccn1CC(=O)NCc2ccccc2
• InChI: 1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
• InChI key: CULUWZNBISUWAS-UHFFFAOYSA-N

Description

General description

N-Benzyl-2-nitro-1H-imidazole-1-acetamide (Benznidazole) is a nitro-heterocyclic compound. It is widely employed drug for the treatment of Chagas disease. It exhibits three polymorphic forms..

Application

N-Benzyl-2-nitro-1H-imidazole-1-acetamide (Benznidazole) may be used as reference drug for the extraction of guaianolide from the aerial parts of Tanacetum parthenium and to evaluate its in vitro antiprotozoal activity.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves