This material is considered insoluble in water. The recommended solvent is acetic acid up to 50 mg/mL or an alcohol such as ethanol or methanol.
14690
Bis(cyclohexanone)oxaldihydrazone
for spectrophotometric det. of Cu, ≥99.0%
Synonym(s):
Cuprizon, Cuprizone, Oxalic acid bis(cyclohexylidenehydrazide)
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| Size/SKU | Availability | Price |
|---|---|---|
25 g | Available to ship TODAY | $98.90 |
100 g | Available to ship TODAY | $278.00 |
About This Item
Empirical Formula (Hill Notation):
C14H22N4O2
CAS Number:
Molecular Weight:
278.35
UNSPSC Code:
41116105
NACRES:
NA.21
PubChem Substance ID:
EC Number:
206-729-2
Beilstein/REAXYS Number:
2388004
MDL number:
$98.90
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Quality Segment
assay
≥99.0% (N), ≥99.0%
form
powder
quality
for spectrophotometric det. of Cu
technique(s)
UV/Vis spectroscopy: suitable
mp
210-214 °C
SMILES string
O=C(N\N=C1\CCCCC1)C(=O)N\N=C2/CCCCC2
InChI
1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
InChI key
DSRJIHMZAQEUJV-UHFFFAOYSA-N
General description
Cuprizone (Bis(cyclohexanone)oxaldihydrazone) is a physically unstable compound and is a well-known neurotoxic agent.
Application
Cuprizone (Bis(cyclohexanone)oxaldihydrazone) was used for toxic demyelination in the central nervous system in order to investigate the pathobiology of remyelination in the corpus callosum, so as to study the human demyelinating diseases such as multiple sclerosis. It was also used a model to study components of neuroinflammation.
Other Notes
In the presence of a copper salt, this ligand catalyzes Ullmann-type C-N bond forming reactions under mild, aqueous conditions.
For the spectrophotometric determination of Cu(II)
1 of 1
This Item | ||
|---|---|---|
| description for spectrophotometric det. of Cu, ≥99.0% | description ≥95% (TLC) | description - |
| technique(s) UV/Vis spectroscopy: suitable | technique(s) titration: suitable | technique(s) - |
| form powder | form powder | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level - |
| assay ≥99.0% (N) | assay ≥95% (TLC) | assay - |
| mp 210-214 °C | mp 210-214 °C (lit.) | mp - |
| quality for spectrophotometric det. of Cu | quality - | quality - |
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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is the Bis(cyclohexanone)oxaldihydrazone soluble in water?
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