P9380

Pyridoxamine dihydrochloride

analytical standard, ≥98%

• Synonym(s): 4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride
• Empirical Formula (Hill Notation): C₈H₁₂N₂O₂ · 2HCl
• CAS Number: 524-36-7
• Molecular Weight: 241.11
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329820346
• EC Number: 208-357-6
• Beilstein/REAXYS Number: 3632748
• MDL number: MFCD00012808

Properties

• biological source: synthetic (organic)
• Quality Segment: 200
• grade: analytical standard
• assay: ≥98%
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• color: white to off-white
• mp: 224-226 °C (dec.) (lit.)
• application(s): vitamins, nutraceuticals, and natural products
• format: neat
• storage temp.: −20°C
• SMILES string: Cl[H].Cl[H].Cc1ncc(CO)c(CN)c1O
• InChI: 1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H
• InChI key: HNWCOANXZNKMLR-UHFFFAOYSA-N

Description

General description

Pyridoxamine dihydrochloride is a salt and amine form of pyridoxamine, which belongs to the family of vitamin B₆ compounds. Pyridoxamine occurs naturally in animal-based food products. Its deficiency in humans potentially causes sideroblastic anemia, weakness, insomnia, and neurological disorders. It has been reported to be effective against diabetic nephropathy.

Application

Pyridoxamine dihydrochloride analytical standard can be used as follows:

• Combined analysis of eight water-soluble vitamins along with their different forms by liquid chromatography combined with isotope-dilution mass spectrometry (IDMS) in different fortified food samples
• Simultaneous determination of eleven water-soluble B vitamins by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in ultrafiltrate samples
• Multi-residue analysis of total thiamine, total riboflavin, total pyridoxine, and total niacin in infant formula and related nutritional products by enzymatic digestion followed by LC-MS-MS determination as per AOAC Official Method 2015.14
• LC/MS-MS based assay of seven different vitamers of vitamin B₃ and vitamin B₆ in 40 human hair samples

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Storage Class: 11 - Combustible Solids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves