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Carbamyl-β-methylcholine chloride

Name: Carbamyl-β-methylcholine chloride
Brand: SIGMA
Price: 241 USD
Availability: InStock

≥99% (TLC), crystalline

Synonym(s):

Bethanechol chloride

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Pack Size	SKU	Availability	Price
5 g		Available to ship onMarch 24, 2026fromMILWAUKEE	$241.00

About This Item

Linear Formula:

C₇H₁₇N₂O₂Cl

CAS Number:

590-63-6

Molecular Weight:

196.68

NACRES:

NA.25

PubChem Substance ID:

24277823

UNSPSC Code:

41116107

EC Number:

209-686-8

MDL number:

MFCD00055224

Assay:

≥99% (TLC)

Form:

crystalline

Quality level:

100

$241.00

Available to ship onMarch 24, 2026Details

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Quality Level

100

assay

≥99% (TLC)

form

crystalline

color

white

solubility

H₂O: 1.7 g/mL (stable for several days at 4°C.), ethanol: 80 mg/mL (stable for several days at 4°C.)

storage temp.

2-8°C

SMILES string

Cl.CC(C[N](C)(C)C)OC(N)=O

InChI

1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H

InChI key

AIRHOJQHGLTTTB-UHFFFAOYSA-N

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This Item	T4376	A0779	B107
Sigma-Aldrich C5259 Carbamyl-β-methylcholine chloride	Sigma-Aldrich T4376 N-p-Tosyl-L-phenylalanine chloromethyl ketone	Sigma-Aldrich A0779 p-Aminoclonidine hydrochloride	Sigma-Aldrich B107 L-BMAA hydrochloride
form crystalline	form powder	form solid	form powder
assay ≥99% (TLC)	assay ≥97% (TLC)	assay -	assay ≥97% (NMR)
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C
solubility H₂O: 1.7 g/mL (stable for several days at 4°C.), ethanol: 80 mg/mL (stable for several days at 4°C.)	solubility DMSO: >10 mg/mL (stable for several months at 4°C.), ethanol: 20 mg/mL	solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.4 mg/mL (Solutions may be stored for several days at 4 °C), boiling water: 100 mg/mL (Solutions may be stored for several days at 4 °C), 0.1 M HCl: soluble (Solutions may be stored for several days at 4 °C), methanol: soluble (Solutions may be stored for several days at 4 °C)	solubility H₂O: soluble (solutions may be stored for several days at 4 °C)
color white	color white	color white	color white to beige

General description

Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.

Application

Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay.[1] It has also been used in concentration-response studies with isolated atrial preparation.

Biochem/physiol Actions

Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine. It induces smooth muscle tension in the bladder. Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells. Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.

Disclaimer

Hygroscopic.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Pharmacology for the Primary Care Provider, 380-380 (2008)

Remodeling of cardiac cholinergic innervation and control of heart rate in mice with streptozotocin-induced diabetes

Mabe AM and Hoover DB

Autonomic Neuroscience : Basic & Clinical, 162(1-2), 24-31 (2011)

[A pilot trial on the treatment of gastroesophageal reflux-related cough in infants].

Darryl J Adamko et al.

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 14(5), 321-327 (2012-05-23)

Diagnosing asthma in infancy is largely made on the basis of the symptoms of cough and wheezing. A similar presentation can be seen in neurologically normal infants with excessive gastroesophageal reflux (GER). There are no randomized placebo controlled studies in

Penn Clinical Manual of Urology, 454-454 (2014)

Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function.

Jagmohan Singh et al.

Gastroenterology, 143(5), 1308-1318 (2012-08-07)

Patients with systemic sclerosis (SSc) have impairments in gastrointestinal smooth muscle function. The disorder has been associated with circulating antibodies to cholinergic muscarinic the type-3 receptor (M(3)-R). We investigated whether it is possible to neutralize these antibodies with pooled human

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Global Trade Item Number

SKU	GTIN
C5259-100G	04061832861913
C5259-5G	04061833501900

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