Skip to Content
MilliporeSigma

D2629

6-(Dimethylamino)purine

≥98%, synthetic (organic), powder

Synonym(s):

6-DMAP, N6,N6-Dimethyladenine

Slide 1 of 5
Sign In to View Organizational & Contract Pricing

Select a Size

100 MG

$62.10

250 MG

$101.00

500 MG

$152.15

1 G

$295.00

$62.10

Estimated to ship onDecember 01, 2025Details

About This Item

Empirical Formula (Hill Notation):
C7H9N5
CAS Number:
938-55-6
Molecular Weight:
163.18
Beilstein/REAXYS Number:
7634
EC Number:
213-344-3
MDL number:
MFCD00005573
UNSPSC Code:
41106305
PubChem Substance ID:
24893701
NACRES:
NA.51

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

6-(Dimethylamino)purine, ≥98%

biological source

synthetic (organic)

assay

≥98%

form

powder

mp

259-262 °C (lit.)

solubility

water: 50 mg/mL, clear to hazy, colorless to light yellow

storage temp.

−20°C

SMILES string

CN(C)c1ncnc2[nH]cnc12

InChI

1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)

InChI key

BVIAOQMSVZHOJM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
A4660P713067619
6-(Dimethylamino)purine ≥98%

Sigma-Aldrich

D2629

6-(Dimethylamino)purine

6-Thioguanine Hybri-Max™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

Sigma-Aldrich

A4660

6-Thioguanine

Puromycin aminonucleoside

Sigma-Aldrich

P7130

Puromycin aminonucleoside

6-Benzylaminopurine PESTANAL®, analytical standard

Supelco

67619

6-Benzylaminopurine

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

biological source

-

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

100

form

powder

form

lyophilized powder

form

powder

form

-

assay

≥98%

assay

~98%

assay

-

assay

≥99.0% (HPLC)

storage temp.

−20°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

solubility

water: 50 mg/mL, clear to hazy, colorless to light yellow

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy

solubility

H2O: soluble 50 mg/mL

solubility

-

General description

6-(Dimethylamino)purine (6-DMAP) is a purine-based metabolite with two condensed heterocyclic rings and two methyl groups linked to the amino group of the purine unit of adenine.[1]

Application

6-(Dimethylamino)purine has been used:
  • as a supplement in GR-1 aa medium (bovine medium) for parthenogenetic activation of bovine oocytes to study its potential for embryo development[2]
  • in the activation step during the production of nuclear transfer embryos[3]
  • as a supplement in HCR2aa medium to activate interspecies embryos derived from interspecies somatic cell nuclear transfer (iSCNT) technique[4]

Biochem/physiol Actions

6-(Dimethylamino)purine (6-DMAP) is a protein kinase and cyclin-dependent kinase inhibitor.[1] It acts as a secondary metabolite and mediates RNA modification. 6-DMAP is a potent cytokinetic inhibitor and is used in parthenogenesis and meiosis studies. It is also used to promote pronuclei formation in mammalian oocytes. 6-DMAP is a dual fluorescence molecule according to femtosecond fluorescence up-conversion spectroscopy studies.[1]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCZ7011
0000464933
0000464933
0000464932
0000464932

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Marcin Szpila et al.
Scientific reports, 9(1), 11859-11859 (2019-08-16)
Postovulatory ageing of mammalian oocytes occurs between their ovulation and fertilization and has been shown to decrease their developmental capabilities. Aged oocytes display numerous abnormalities, including altered Ca2+ signalling. Fertilization-induced Ca2+ oscillations are essential for activation of the embryonic development
Patrick Imesch et al.
Journal of ovarian research, 6, 30-30 (2013-04-20)
Oocyte in vitro maturation (IVM) and cryopreservation at the time of routine ovarian tissue freezing may be offered to cancer patients as an additional option for fertility preservation. This study aimed to investigate the developmental capacity of oocytes isolated from
Justine Collier
Current opinion in microbiology, 12(6), 722-729 (2009-09-29)
N(6)-methyl-adenines can serve as epigenetic signals for interactions between regulatory DNA sequences and regulatory proteins that control cellular functions, such as the initiation of chromosome replication or the expression of specific genes. Several of these genes encode master regulators of
Wiebke Garrels et al.
PloS one, 6(8), e23573-e23573 (2011-09-08)
Genetic engineering can expand the utility of pigs for modeling human diseases, and for developing advanced therapeutic approaches. However, the inefficient production of transgenic pigs represents a technological bottleneck. Here, we assessed the hyperactive Sleeping Beauty (SB100X) transposon system for
Gaid Le Beux et al.
Theriogenology, 60(6), 1049-1058 (2003-08-26)
Improvement of the ability to maintain germinal vesicle stage oocytes in vitro is important for the acquisition of developmental competence. Maintaining oocytes at this stage without damaging their quality would allow synchronization of maturation and homogenization of the oocytes population.
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service