GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
Synonyms:
Species:
Human GABRG3 (2567), Mouse Gabrg3 (14407), Rat Gabrg3 (79211), naked mole-rat Gabrg3 (101712623), domestic guinea pig Gabrg3 (100729690), domestic cat GABRG3 (101094182), sheep GABRG3 (101108521), dog GABRG3 (488685), cow GABRG3 (613670), chicken GABRG3 (770097)
UniProtKB ID:
Gene ID:
- Human(2567) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
- Mouse(14407) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
- Rat(79211) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- naked mole-rat(101712623) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- domestic guinea pig(100729690) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- domestic cat(101094182) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- sheep(101108521) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- dog(488685) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- cow(613670) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- chicken(770097) gamma-aminobutyric acid (GABA) A receptor, gamma 3
- Zebrafish(567057) gamma-aminobutyric acid (GABA) A receptor, gamma 3
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Small Molecule - Agonist
Product Number
Description
Species
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Chlordiazepoxide hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Oxazepam for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Lorazepam for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human