Passa al contenuto
Merck

HLA-DPB1

major histocompatibility complex, class II, DP beta 1

Sinonimi:
DPB1, HLA-DP, HLA-DP1B, HLA-DPB
Specie:
Human HLA-DPB1 (3115)
ID UniProtKB:
P04440, A0PFJ7, A5I886, A8YPB3, B5U8B4, B7VF80, B7VF87, B8ZX68
ID gene:
  • Human(3115) Summary: HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
HPA011078
Anti-HLA-DPB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
ZRB2252
Anti-HLA-DPB1 Antibody, clone 1E16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
SAB5500119
Anti-HLA-DP beta 1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP229, affinity isolated antibody,
Reattività con
human
Applicazione
flow cytometry
immunohistochemistry
HPA058509
Anti-HLA-DPB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence

esiRNA

Numero di prodotto
Descrizione
Specie
EHU128451
MISSION® esiRNA, targeting human HLA-DPB1 (2),
Specie
human
EHU116891
MISSION® esiRNA, targeting human HLA-DPB1 (1),
Specie
human