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258385

Protoporphyrin IX disodium salt

≥90% (HPLC)

Synonym(s):

3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid disodium salt, Depocolin-S, Ooporphyrin disodium salt

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Size/SKUAvailabilityPrice
250 mg

Available to ship TODAYfromMILWAUKEE

$55.70
1 g

Available to ship TODAYfromMILWAUKEE

$194.00
5 g

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$605.00

About This Item

Empirical Formula (Hill Notation):
C34H32N4Na2O4
CAS Number:
Molecular Weight:
606.62
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
256-815-9
Beilstein/REAXYS Number:
5227034
MDL number:

$55.70


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Quality Segment

assay

≥90% (HPLC)

form

powder

λmax

406 nm

storage temp.

2-8°C

SMILES string

[Na+].[Na+].Cc1c(CCC([O-])=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C=C)c5C)c(C=C)c4C)c(C)c3CCC([O-])=O

InChI

1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,36-37H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

JZRNDUPVNXWZDY-HXFTUNQESA-L

Application

Protoporphyrin disodium salt (PpIX) was used as a dye content for fluorescence spectroscopic characterization in a study. The cytotoxic effect of PpIX on sarcoma 180 solid tumors cells was reported in a study.

Features and Benefits

  • High purity (≥90% HPLC)
  • Operates effectively within a wavelength range of 403-409 nm
  • Exhibits a high extinction coefficient of ≥120,000
  • Available in multiple pack sizes

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This Item
P8293282820SML0804
description

≥90% (HPLC)

description

≥95%

description

guanylate cyclase inhibitor

description

≥96% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥90% (HPLC)

assay

≥95%

assay

≥92% (HPLC)

assay

≥96% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

λmax

406 nm

λmax

-

λmax

426 nm

λmax

-


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–2 of 2 Questions  
  1. To study interaction of porphyrin with a protein, how should a solution of this compound be made for flourescence quenching?

    1 answer
    1. This is not an application that is tested internally, but there is evidence in literature (Iwunze MO. The fluorescence study of the quenching of nanoemulsion by protoporphyrin IX (PPIX). Material Sci & Eng. 2022;6(3):97‒99. DOI: 10.15406/mseij.2022.06.00185) that concentrations between 6.45 x 10-7 M to 3.24 x 10-6 M PPIX are effective for quenching. Another author describes the quenching of protein fluorescence by PPIX by using a solution concentration range of 1×10−5 M to 3×10−4 M excited at 280 nm and 1x10−5 M to 3×10−4 M excited at 295 nm (Characteristics of the Protoporphyrin IX Binding Sites on Human Serum Albumin Using Molecular Docking, Molecules 2016, 21(11), 1519).

      Helpful?

  2. What is the water solubility of PPIX-disodium?

    1 answer
    1. This chemical is known to be soluble in chloroform or methanol and slightly soluble in water. The concentration at which this product is solubilized is not determined.

      Helpful?

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