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412422

PAMAM dendrimer, ethylenediamine core, generation 3.0 solution

20 wt. % in methanol

Synonym(s):

Starburst PAMAM-G 3

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5 g

Available to ship TODAYfromMILWAUKEE

$489.00
25 g
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$2,070.00

About This Item

Linear Formula:
[NH2(CH2)2NH2]:(G=3);dendri PAMAM(NH2)32
CAS Number:
Molecular Weight:
6908.84
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:

$489.00


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description

amino surface groups

Quality Segment

form

liquid

mol wt

generation 3.0

feature

core type ethylenediamine core (2-carbon core)

concentration

20 wt. % in methanol

no. Surface Groups

32

refractive index

n20/D 1.367

bp

64.7 °C

density

0.863 g/mL at 25 °C

storage temp.

2-8°C

General description

PAMAM dendrimer is a symmetrical polymer with a large number of terminal groups that can easily bind to biomolecules due to their biocompatibility and affinity. These dendrimers have a multivalent surface that contains envelopes and various active sites at the core with the attached dendrons. They are highly branched nanoscale polymers that are extensively used in the field of biomedicine for targeted drug delivery.

Application

PAMAM dendrimers can be used as transfection agents for the delivery of nucleic acids. For example, it can be used in the pulmonary delivery of siRNA directed against tumor necrosis factor (TNF).

Physical form

Contains 32 surface primary amino groups

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

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description

20 wt. % in methanol

description

10 wt. % in methanol

description

5 wt. % in methanol

description

20 wt. % in methanol

refractive index

n20/D 1.367

refractive index

n20/D 1.348

refractive index

-

refractive index

n20/D 1.362

form

liquid

form

solution

form

liquid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

density

0.863 g/mL at 25 °C

density

0.813 g/mL at 25 °C

density

0.797 g/mL at 25 °C

density

0.82 g/mL at 25 °C

description

amino surface groups

description

amino surface groups

description

amino surface groups

description

amino surface groups

no. Surface Groups

32

no. Surface Groups

64

no. Surface Groups

128

no. Surface Groups

8


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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