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ALD00558

1-((3,5-Difluorophenyl)sulfonyl)bicyclo[1.1.0]butane

95%

Synonym(s):

Baran cyclobutylation reagent

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Size/SKUAvailabilityPrice
500 mg

Available to ship TODAYfromMILWAUKEE

$480.00

About This Item

Empirical Formula (Hill Notation):
C10H8F2O2S
Molecular Weight:
230.23
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
Assay:
95%
Form:
powder or crystals

$480.00


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Quality Segment

assay

95%

form

powder or crystals

reaction suitability

reaction type: C-C Bond Formation

storage temp.

2-8°C

General description

1-((3,5-Difluorophenyl)sulfonyl)bicyclo[1.1.0]butane can be used as a cyclobutylation agent to introduce bicyclobutane group onto a variety of amines and thiols without affecting other functional groups.

Application

The following "spring-loaded" electrophile is a convenient reagent for the installation of cyclobutane to primary and secondary amines. This product is one of several synthetically useful reagents reported by Baran and coworkers on strain-release amination.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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