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BP837

Cetirizine hydrochloride

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Cetirizine dihydrochloride, [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

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Size/SKUAvailabilityPrice
100 mg
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$254.00

About This Item

Empirical Formula (Hill Notation):
C21H25ClN2O3 · 2HCl
CAS Number:
Molecular Weight:
461.81
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:

$254.00


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grade

pharmaceutical primary standard

API family

cetirizine

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

OC(COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1)=O.[H]Cl.[H]Cl

InChI

1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H

InChI key

PGLIUCLTXOYQMV-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cetirizine hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Cetirizine Capsules
  • Cetirizine Oral Solution
  • Cetirizine Tablets
  • Biochem/physiol Actions

    Cetirizine hydrochloride is a non-sedating type histamine H1-receptor antagonist.
    Cetirizine hydrochloride is an orally active and selective H1-receptor antagonist. Antihistaminic; Piperazines. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    This Item
    PHR16561102929C0980650
    description

    British Pharmacopoeia (BP) Reference Standard

    description

    Pharmaceutical Secondary Standard; Certified Reference Material

    description

    United States Pharmacopeia (USP) Reference Standard

    description

    European Pharmacopoeia (EP) Reference Standard

    grade

    pharmaceutical primary standard

    grade

    certified reference material, pharmaceutical secondary standard

    grade

    pharmaceutical primary standard

    grade

    pharmaceutical primary standard

    manufacturer/tradename

    BP

    manufacturer/tradename

    -

    manufacturer/tradename

    USP

    manufacturer/tradename

    EDQM

    application(s)

    pharmaceutical
    pharmaceutical small molecule

    application(s)

    pharmaceutical (small molecule)

    application(s)

    pharmaceutical (small molecule)

    application(s)

    pharmaceutical (small molecule)

    shelf life

    limited shelf life, expiry date on the label

    shelf life

    -

    shelf life

    -

    shelf life

    -

    format

    neat

    format

    neat

    format

    neat

    format

    neat

    form

    solid

    form

    -

    form

    -

    form

    -


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    pictograms

    Exclamation mark

    signalword

    Warning

    hcodes

    Hazard Classifications

    Acute Tox. 4 Oral

    Storage Class

    11 - Combustible Solids

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable



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    Questions

    1–2 of 2 Questions  
    1. How can I determine the shelf life / expiration / retest date of this product?

      1 answer
      1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
        For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
        For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
        For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

        Helpful?

    2. How is shipping temperature determined? And how is it related to the product storage temperature?

      1 answer
      1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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