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H4784

Heparin sodium salt from porcine intestinal mucosa

≥180 USP units/mg

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Size/SKUAvailabilityPrice
250 mg
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$94.60
1 g
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$353.00

About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:

$94.60


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Diagnostics Manufacturers should use alternative grade product: SRE0027

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biological source

Porcine intestinal mucosa

Quality Segment

form

powder

specific activity

≥180 USP units/mg

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

cation traces

Ca: ≤20 ppm

storage temp.

2-8°C

SMILES string

[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O

InChI key

JRTRSJGZMRQDHI-UHFFFAOYSA-N

General description

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Analysis Note

Low calcium content

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This Item
2106H5515SRE0027
description

≥180 USP units/mg

description

endotoxin, free

description

≥150 IU/mg (dry basis)

description

-

form

powder

form

powder

form

powder

form

powder

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

solubility

alcohol: insoluble, diethyl ether: insoluble, benzene: insoluble, water: soluble 50 g/L, acetone: insoluble, chloroform: insoluble

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL (colorless to faint yellow)

storage temp.

2-8°C

storage temp.

room temp

storage temp.

room temp

storage temp.

-

cation traces

Ca: ≤20 ppm

cation traces

-

cation traces

-

cation traces

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

400

biological source

Porcine intestinal mucosa

biological source

Porcine intestinal mucosa

biological source

Porcine intestinal mucosa

biological source

Porcine (mucosa)


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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–8 of 8 Questions  
  1. How much Heparin sodium salt, is used to prevent coagulation?

    1 answer
    1. It is suggested to use 15 to 30 units per mL of blood.

      Helpful?

  2. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

  3. What concentration of Product H4784, Heparin sodium salt, is used in cell culture for the cultivation of human epidermal melanocytes in absence of phorbol esters?

    1 answer
    1. Heparin is used at a concentration of 1 ng/mL, according to Picot, J., Human Cell Culture: Methods in Molecular Medicine, 2nd ed., (Humana Press Inc., 2005) pp. 13-28.

      Helpful?

  4. What is the pH of a 1% solution of Product H4784, Heparin sodium salt?

    1 answer
    1. The pH of 1% solution of heparin sodium salt is typically in the range of 6.0 to 7.5.

      Helpful?

  5. What concentration of Heparin sodium salt, can I use to inhibit RNAse activity?

    1 answer
    1. Heparin has been used at concentrations ranging from 100 to 500 μg/mL. This has been reported in the J. Biol. Chem., 248, 2095 (1973).

      Helpful?

  6. What is the best way to sterilize Heparin sodium salt?

    1 answer
    1. Although solutions may be autoclaved at 121 °C for 5 to 10 minutes, we generally recommend sterile filtration. This is because prolonged autoclaving may have an effect on its activity.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  8. What is the molecular weight of Heparin sodium salt?

    1 answer
    1. Heparin is a mixture of polyanion chains having molecular weights ranging from 6,000 to 30,000 Daltons, with most chains in the range of 17,000 to 19,000 Daltons.

      Helpful?

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