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PHR1572

Oxymetazoline Hydrochloride

certified reference material, pharmaceutical secondary standard

Synonym(s):

Oxymetazoline hydrochloride, 2-(3-Hydroxy-2,6-dimethyl-4-t-butylbenzyl)-2-imidazoline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H24N2O · HCl
CAS Number:
2315-02-8
Molecular Weight:
296.84
NACRES:
NA.24
PubChem Substance ID:
329823480
UNSPSC Code:
41116107
EC Number:
219-015-0
MDL number:
MFCD00058147
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Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. O0290000, traceable to USP 1486004

API family

oxymetazoline

CofA

current certificate can be downloaded

packaging

pkg of 10 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C

InChI

1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H

InChI key

BEEDODBODQVSIM-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxymetazoline hydrochloride belongs to the category of non-selective adrenergic drugs commonly used as eye and nose drops.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Oxymetazoline hydrochloride may be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations using spectrophotometric technique.

Biochem/physiol Actions

Oxymetazoline hydrochloride is a partial α2A-adrenoceptor agonist; agonist at 5-HT1A, 5-HT1B, and 5-HT1D serotonin receptors. It is a mixed agonist-antagonist at 5-HT1C serotonin receptors.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAB5024 in the slot below. This is an example certificate only and may not be the lot that you receive.

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This Item
1486004O0290000PHR1853
Oxymetazoline Hydrochloride certified reference material, pharmaceutical secondary standard

Supelco

PHR1572

Oxymetazoline Hydrochloride

Oxymetazoline hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1486004

Oxymetazoline hydrochloride

Oxymetazoline hydrochloride European Pharmacopoeia (EP) Reference Standard

O0290000

Oxymetazoline hydrochloride

Tetrahydrozoline hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1853

Tetrahydrozoline hydrochloride

description

certified reference material, pharmaceutical secondary standard

description

United States Pharmacopeia (USP) Reference Standard

description

European Pharmacopoeia (EP) Reference Standard

description

Pharmaceutical Secondary Standard; Certified Reference Material

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

gas chromatography (GC): suitable, HPLC: suitable

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

Quality Level

300

Quality Level

-

Quality Level

-

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical secondary standard, certified reference material

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-30°C

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pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

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Certificates of Analysis (COA)

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