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G8923

GANT58

≥98% (HPLC)

Synonym(s):

2,3,4,5-Tetra(4-pyridyl)thiophene, 4,4′,4′′,4′′′-Thiene-2,3,4,5-tetrayltetrapyridine

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About This Item

Empirical Formula (Hill Notation):
C24H16N4S
CAS Number:
64048-12-0
Molecular Weight:
392.48
NACRES:
NA.77
PubChem Substance ID:
329799981
UNSPSC Code:
51111800
MDL number:
MFCD01103196
Assay:
≥98% (HPLC)
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Quality Segment

assay

≥98% (HPLC)

color

white to pale yellow

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

c1cc(ccn1)-c2sc(-c3ccncc3)c(-c4ccncc4)c2-c5ccncc5

InChI

1S/C24H16N4S/c1-9-25-10-2-17(1)21-22(18-3-11-26-12-4-18)24(20-7-15-28-16-8-20)29-23(21)19-5-13-27-14-6-19/h1-16H

InChI key

USWLOKMMUTWFMD-UHFFFAOYSA-N

Biochem/physiol Actions

GANT58 is a Hedgehog signaling pathway inhibitor.
GANT58 is a Hedgehog signaling pathway inhibitor. GANT58 inhibits the hedgehog signaling pathway downstream of Smo. GANT58 inhibits Gli transcriptional activity, and reduces cellular levels of the Hh pathway components Gli1, Shh, and patched.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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