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SMB00802

Bavachin

from Psoralea coryfolia, ≥97% (HPLC)

Synonym(s):

(2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one, 4′,7-Dihydroxy 6-(3-methyl 2-butenyl)flavanone, Corylifolin

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Size/SKUAvailabilityPrice
5 mg
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MXP 3,491.00

About This Item

Empirical Formula (Hill Notation):
C20H20O4
CAS Number:
Molecular Weight:
324.37
UNSPSC Code:
12352205
NACRES:
NA.28
MDL number:

MXP 3,491.00


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assay

≥97% (HPLC)

form

powder

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

O1C(CC(=O)c3c1cc(c(c3)CC=C(C)C)O)c2ccc(cc2)O

InChI

1S/C20H20O4/c1-12(2)3-4-14-9-16-18(23)11-19(24-20(16)10-17(14)22)13-5-7-15(21)8-6-13/h3,5-10,19,21-22H,4,11H2,1-2H3

InChI key

OAUREGNZECGNQS-UHFFFAOYSA-N

General description

Bavachin is soluble in DMSO at 30 mg/mL. Bavachin is not water soluble.

Biochem/physiol Actions

Bavachin is a flavonoid isolated from seeds of Psoralea corylifolia. It is a phytoestrogen that activates ERα and ERβ (EC50s = 320 and 680 nM, respectively), stimulates osteoblast proliferation and differentiation, and prevents bone loss following ovariectomy in rats.[1]

Bavachin is an inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT). The IC50 value of bavachin was reported to be 86.0 μM in ACAT assay system using rat liver microsome.[2]

Bavachin is also reported to increase insulin-induced glucose uptake by differentiated adipocytes and myoblasts.[3]

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This Item
SMB00100SML1450PHL82483
assay

≥97% (HPLC)

assay

≥95% (LC/MS-ELSD)

assay

≥98% (HPCE)

assay

≥98.0% (HPLC)

form

powder

form

solid

form

powder

form

-

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

-

application(s)

food and beverages

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C


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Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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