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SML1542

Sitamaquine tosylate

≥98% (HPLC)

Synonym(s):

6-Methoxy-8-(6-diethylaminohexylamine)-4-methylquinoline tosylate, N-[6-(Diethylamino)hexyl]-6-methoxy-4-methylquinolin-8-amine tosylate, N1,N1-Diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamine tosylate, NSC 2452, WR-6026

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$131.00
$111.35
25 mg

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$410.00

About This Item

Empirical Formula (Hill Notation):
C21H33N3O · C7H8O3S
CAS Number:
Molecular Weight:
515.71
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$111.35

List Price$131.00Save 15%
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Estimated to ship onSeptember 08, 2026Details


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 15 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=C(C=C(OC)C=C2NCCCCCCN(CC)CC)C2=NC=C1.CC3=CC=C(S(=O)(O)=O)C=C3

InChI

1S/C21H33N3O.C7H8O3S/c1-5-24(6-2)14-10-8-7-9-12-22-20-16-18(25-4)15-19-17(3)11-13-23-21(19)20;1-6-2-4-7(5-3-6)11(8,9)10/h11,13,15-16,22H,5-10,12,14H2,1-4H3;2-5H,1H3,(H,8,9,10)

InChI key

LOBPWLFCZDGYKW-UHFFFAOYSA-N

Biochem/physiol Actions

Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities.
Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishmania parasites. Sitamaquine potently inhibits respiratory chain complex II (succinate dehydrogenase), which leads to an apoptosis-like death of Leishmania parasites.
Sitamaquine is also known as WR-6026. It is used in the treatment of visceral leishmaniasis.

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This Item
J3955SML3017M5255
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98%

form

powder

form

powder

form

powder

form

-

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

300

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: 15 mg/mL, clear

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 2 mg/mL, clear

solubility

methanol: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

color

white to beige

color

tan

color

white to beige

color

white to yellow-white


Storage Class

11 - Combustible Solids

wgk

WGK 3



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