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219142

5-Bromopyrimidine

97%

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Size/SKUAvailabilityPrice
5 g
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$57.10
25 g
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$99.00

About This Item

Empirical Formula (Hill Notation):
C4H3BrN2
CAS Number:
Molecular Weight:
158.98
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
224-992-1
Beilstein/REAXYS Number:
107326
MDL number:
Assay:
97%
Form:
solid

$57.10


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Quality Segment

assay

97%

form

solid

mp

67-73 °C (lit.)

functional group

bromo

SMILES string

Brc1cncnc1

InChI

1S/C4H3BrN2/c5-4-1-6-3-7-2-4/h1-3H

InChI key

GYCPLYCTMDTEPU-UHFFFAOYSA-N

General description

Rapid nucleophilic displacement reactions of 5-bromopyrimidine with nucleophiles under microwave irradiation has been studied. 5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine.

Application

5-Bromopyrimidine was used in the synthesis of:
  • N-heteroaryl substituted 9-arylcarbazolyl derivatives via palladium-catalyzed aerobic and ligand-free Suzuki reaction
  • (5-(phenylethynyl)pyrimidine) via microwave assisted organic synthesis (MAOS) Sonogashira protocol

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This Item
245844
description

97%

description

95%

assay

97%

assay

95%

Quality Level

100

Quality Level

100

mp

67-73 °C (lit.)

mp

55-57 °C (lit.)

form

solid

form

-

functional group

bromo

functional group

bromo


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Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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