37640
2,8-Quinolinediol
≥99.0% (HPLC)
Synonym(s):
2,8-Dihydroxyquinoline
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| Size/SKU | Availability | Price |
|---|---|---|
1 g | Available to ship TODAY | $48.50 |
About This Item
Empirical Formula (Hill Notation):
C9H7NO2
CAS Number:
Molecular Weight:
161.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
472906
Assay:
≥99.0% (HPLC)
Form:
powder
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Quality Segment
assay
≥99.0% (HPLC)
form
powder
mp
~290 °C (dec.)
SMILES string
Oc1ccc2cccc(O)c2n1
InChI
1S/C9H7NO2/c11-7-3-1-2-6-4-5-8(12)10-9(6)7/h1-5,11H,(H,10,12)
InChI key
ZXZKYYHTWHJHFT-UHFFFAOYSA-N
General description
8-hydroxyquinolin-2(1H)-one has been reported as the tautomeric form of 2,8-quinolinediol. 2,8-Quinolinediol (2,8-Dihydroxyquinoline) has been identified as one of the metabolite of quinolone formed in the culture medium of gram-negative bacteria, Pseudomonas stutzeri.
2,8-Quinolinediol is a quinolone derivative. It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits. Synthesis of 2,8-quinolinediol has been reported. It is reported as one of the six possible forms of 8-hydroxycarbostyril. It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by 1H, 13C and 1H ×13C NMR.It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.
Application
2,8-Quinolinediol is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques. It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma:
- Procaterol
- Indacaterol
1 of 1
This Item | |||
|---|---|---|---|
| description ≥99.0% (HPLC) | description 97% | description ≥95.0% (HPLC) | description ≥98.0% (HPLC) |
| assay ≥99.0% (HPLC) | assay 97% | assay ≥95.0% (HPLC) | assay ≥98.0% (HPLC) |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| mp ~290 °C (dec.) | mp >300 °C (lit.) | mp 158-162 °C | mp 162-164 °C, 161-165 °C (lit.) |
| form powder | form - | form solid | form - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
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