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38827

4,4′-Dimethoxytriphenylmethyl chloride

≥97.0% (HPLC)

Synonym(s):

4,4′-Dimethoxytrityl chloride, Chloro-4,4′-dimethoxytriphenylmethane, DMT, DMT-Cl

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Size/SKUAvailabilityPrice
10 g

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$135.00
50 g

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$563.00

About This Item

Empirical Formula (Hill Notation):
C21H19ClO2
CAS Number:
Molecular Weight:
338.83
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
EC Number:
255-002-6
Beilstein/REAXYS Number:
2471942
MDL number:
Assay:
≥97.0% (HPLC)

$135.00


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Quality Segment

assay

≥97.0% (HPLC)

reaction suitability

reactivity: alcohol reactive, reagent type: protection reagent

mp

123-125 °C

functional group

chloro, phenyl

SMILES string

COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3

InChI

1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3

InChI key

JBWYRBLDOOOJEU-UHFFFAOYSA-N

Gene Information

Application

4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:
  • For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
  • For 10 sulfhydryl group of oligonucleotide analogs as its DMTr thioether.

Other Notes

Useful protecting-group reagent; Removal

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This Item
100013113700D151203
description

≥97.0% (HPLC)

description

95%

description

99%

description

97%

assay

≥97.0% (HPLC)

assay

95%

assay

99%

assay

97%

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

reaction suitability

reactivity: alcohol reactive, reagent type: protection reagent

reaction suitability

reagent type: protection reagent, reactivity: amine reactive, reactivity: alcohol reactive, reactivity: thiol reactive

reaction suitability

-

reaction suitability

-

mp

123-125 °C

mp

119-123 °C (lit.)

mp

144-146 °C (lit.)

mp

118-120 °C (lit.)

Gene Information

human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
rat ... Htr1a(24473), Htr2a(29595)

Gene Information

-

Gene Information

-

Gene Information

-

functional group

phenyl, chloro

functional group

chloro, phenyl

functional group

ketone, chloro

functional group

-


Signal Word

Danger

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class

8B - Non-combustible corrosive hazardous materials

WGK

WGK 3

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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