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394815

N-Maleoyl-β-alanine

97%

Sustainability features

Synonym(s):

3-Maleimidopropionic acid, N-(2-Carboxyethyl)maleimide

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Size/SKUAvailabilityPrice
250 mg

Available to ship TODAYfromMILWAUKEE

$255.00
1 g

Available to ship TODAYfromMILWAUKEE

$538.00

About This Item

Empirical Formula (Hill Notation):
C7H7NO4
CAS Number:
Molecular Weight:
169.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1528952
Assay:
97%
Form:
powder

$255.00


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Quality Segment

assay

97%

form

powder

greener alternative product score

old score: 18
new score: 7
Find out more about DOZN™ Scoring

sustainability

Sustainability features

mp

103-106 °C (lit.)

functional group

carboxylic acid, imide, maleimide

greener alternative category

storage temp.

2-8°C

SMILES string

OC(=O)CCN1C(=O)C=CC1=O

InChI

1S/C7H7NO4/c9-5-1-2-6(10)8(5)4-3-7(11)12/h1-2H,3-4H2,(H,11,12)

InChI key

IUTPJBLLJJNPAJ-UHFFFAOYSA-N

General description

N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies.
We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Less Hazardous Chemical Syntheses”, "Safer Solvents and Auxiliaries" and “Inherently Safer Chemistry for Accident Prevention”. Click here to view its DOZN scorecard.

Application

N-Maleoyl-β-alanine (3-maleimidopropanoic acid, N-(2-carboxyethyl)maleimide)) is the suitable reagent used in the following studies:
  • To decrease the biotin binding affinity of Avd(S16C) (avidin with a single point mutation S16C).
  • As a side chain reactive agent to modify tryptic peptides that result in mass shifts indicating the presence of cysteine residues.
  • To preblock Xenopus laevis oocytes for exposed cysteines used as an expression system in the study of conformational changes in cASIC1a Receptors.
It may be used in the following studies:
  • As a protective agent for keratin fiber in high temperature process.
  • As a non-cleavable maleimido moiety during the synthesis of tetrawalled molecular umbrella-octaarginine conjugates.
  • Synthesis of organotin carboxylates of N-Maleoyl-β-alanine.
  • To functionalize the gold surfaces to interact with cysteine-modified peptide.
  • Preparation of cross-linked dextran–poly(ethylene glycol) hydrogel substrate.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
490091CDS000423752576
description

97%

description

99 atom % 13C

description

AldrichCPR

description

≥99 atom % 13C, ≥98 atom % D, ≥98% (CP)

assay

97%

assay

99% (CP)

assay

-

assay

≥98% (CP)

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

mp

103-106 °C (lit.)

mp

270-275 °C (dec.) (lit.)

mp

-

mp

298-300 °C (subl.) (lit.)

form

powder

form

solid

form

solid

form

solid

greener alternative category

, Re-engineered

greener alternative category

Re-engineered

greener alternative category

-

greener alternative category

Re-engineered,


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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