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422835

2-Chloro-N-(hydroxymethyl)acetamide

98%

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Size/SKUAvailabilityPrice
5 g

Available to ship TODAYfromMILWAUKEE

$60.00

About This Item

Linear Formula:
ClCH2CONHCH2OH
CAS Number:
Molecular Weight:
123.54
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
220-598-9
MDL number:
Assay:
98%

$60.00


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Quality Segment

assay

98%

mp

100-105 °C (lit.)

functional group

amide, hydroxyl

SMILES string

OCNC(=O)CCl

InChI

1S/C3H6ClNO2/c4-1-3(7)5-2-6/h6H,1-2H2,(H,5,7)

InChI key

TXNSZCSYBXHETP-UHFFFAOYSA-N

General description

2-Chloro-N-(hydroxymethyl)acetamide (N-methylolchloracetamide) is a N-hydroxymethyl derivative of chloroacetamide. One of the method reported for its synthesis is by the reaction of 2-chloracetamide with formaldehyde. It has been reported to be a formaldehyde releaser and an infrequent sensitizer to formaldehyde contact allergy. Influence of short and prolonged exposure of 2-chloro-N-(hydroxymethyl)acetamide (as formaldehyde donor/releaser) on lymph node responses has been investigated.

Application

2-Chloro-N-(hydroxymethyl)acetamide (N-hydroxymethylchloroacetamide) may be used as a reagent in the synthesis of 1-(aminomethyl)-2-methoxynaphthalene hydrochloride and as a amidomethylating reagent for N,N-dialkylanilines (Tscherniac-Einhorn reaction).

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This Item
TMT00606OTV000903OTV000647
description

98%

description

-

description

-

description

-

assay

98%

assay

-

assay

-

assay

-

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

mp

100-105 °C (lit.)

mp

-

mp

-

mp

-

functional group

amide

functional group

amide

functional group

ether, amide

functional group

amide, bromo


Pictograms

Corrosion

Signal Word

Danger

Hazard Codes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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