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425834

N-Boc-pyrrole

98%

Synonym(s):

tert-Butyl 1-pyrrolecarboxylate

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Size/SKUAvailabilityPrice
25 mL

Available to ship TODAY

$75.70
100 mL

Available to ship TODAY

$262.00

About This Item

Empirical Formula (Hill Notation):
C9H13NO2
CAS Number:
Molecular Weight:
167.21
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
liquid

$75.70


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Quality Segment

assay

98%

form

liquid

refractive index

n20/D 1.4685 (lit.)

bp

91-92 °C/20 mmHg (lit.)

density

1 g/mL at 25 °C (lit.)

SMILES string

CC(C)(C)OC(=O)n1cccc1

InChI

1S/C9H13NO2/c1-9(2,3)12-8(11)10-6-4-5-7-10/h4-7H,1-3H3

InChI key

IZPYBIJFRFWRPR-UHFFFAOYSA-N

General description

N-Boc-pyrrole is an N-protected pyrrole. It undergoes Diels–Alder reaction with enantiomerically pure allene-1,3-dicarboxylates to form endo-adducts with retention in configurations at two newly generated stereogenic centers. It also undergoes cyclopropanation with methyl phenyldiazoacetate to form both monocyclopropane and dicyclopropane. Its Ir-catalyzed C-H borylation followed by cross coupling with 3-chlorothiophene to form biheterocycle has been reported.

Application

N-Boc-pyrrole was used in the synthesis of 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid by treating with n-BuLi and subsequent reaction with trimethyl borate.
It may be used as starting material in the synthesis of the following:
  • tropane drivatives
  • N-boc-2-(4-methoxyphenyl)pyrrole
  • N-boc-pyrrol-2-ylboronic acid

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This Item
427055715387696447
description

98%

description

97%

description

97%

description

97%

assay

98%

assay

97%

assay

97%

assay

97%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

liquid

form

liquid

form

solid

form

powder

density

1 g/mL at 25 °C (lit.)

density

0.977 g/mL at 25 °C (lit.)

density

-

density

-

bp

91-92 °C/20 mmHg (lit.)

bp

80 °C/0.2 mmHg (lit.)

bp

-

bp

-

refractive index

n20/D 1.4685 (lit.)

refractive index

n20/D 1.449 (lit.)

refractive index

-

refractive index

-


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

167.0 °F - closed cup

Flash Point (°C)

75 °C - closed cup

PPE (personal protective equipment)

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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