This product is listed as suitable for peptide synthesis. It may be okay for cell culture, but it is not tested with that application in mind, so the suitability would need to be determined by the end user. What is tested can be found on the product COA, an example of which can be found in the 'Documentation' section of the product page.
452483
1-Methyl-D-tryptophan
95%, for peptide synthesis
Synonym(s):
(2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, D-(+)-1-Methyltryptophan
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| Size/SKU | Availability | Price |
|---|---|---|
250 mg | Available to ship TODAY | $55.10 |
1 g | Available to ship TODAY | $169.00 |
10 g | Available to ship TODAY | $1,100.00 |
About This Item
Empirical Formula (Hill Notation):
C12H14N2O2
CAS Number:
Molecular Weight:
218.25
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
MDL number:
eCl@ss:
32129103
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Product Name
1-Methyl-D-tryptophan, 95%
Quality Segment
assay
95%
form
lumps and powder
optical activity
[α]22/D +12.4°, c = 2 in acetic acid
reaction suitability
reaction type: solution phase peptide synthesis
mp
242-245 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12
InChI
1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1
InChI key
ZADWXFSZEAPBJS-SNVBAGLBSA-N
Application
Used to prepare a number of natural products including macroline alkaloids using the Pictet-Spengler reaction of tryptophan esters with aldehydes also used in the synthesis of 1-substituted indolactam precursors.
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This Item | ||
|---|---|---|
| description 95% | description 97% | description ≥98.0% (HPLC) |
| form lumps and powder | form - | form powder |
| assay 95% | assay 97% | assay ≥98.0% (HPLC) |
| mp 242-245 °C (lit.) | mp 86-89 °C (lit.) | mp 282-285 °C (dec.) (lit.) |
| optical activity [α]22/D +12.4°, c = 2 in acetic acid | optical activity [α]20/D +18.5°, c = 1 in methanol | optical activity - |
| Quality Level 100 | Quality Level 100 | Quality Level 200 |
| reaction suitability reaction type: solution phase peptide synthesis | reaction suitability reaction type: solution phase peptide synthesis | reaction suitability - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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I have a question regarding 1-methyl-D-tryptophan (452483). Is this suitable for cell culture study purpose? Thank you.
1 answer-
Helpful?
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What is Product 452483, 1-Methyl-D-tryptophan, soluble in?
1 answer-
While we don't test the solubility of this product directly, we do have to dissolve it in acetic acid in order to test the optical rotation. We would also expect this to be soluble in a dilute hydrochloric acid solution (50mg/mL in 5N HCl). Both heat and sonication may be required in order to prepare a homogenous solution. Also, based on our experience with the DL (Product No. 860646) and L (Product No. 447439) forms, we would expect that dilute sodium hydroxide would also be a potential solvent (1g/100mL of 1M NaOH).
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How should Product 452483, 1-Methyl-D-tryptophan, be stored?
1 answer-
This material is stable at room temperature without any special handling precautions.
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What is the solution stability of Product 452483, 1-Methyl-D-tryptophan?
1 answer-
Unfortunately, we do not perform solution stability testing on this item or have experience with storing tryptophan solutions, so we would recommend making a fresh batch with each use.
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