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759902

Dibenzocyclooctyne-PEG4-acid

for Copper-free Click Chemistry

Synonym(s):

Polyethylene glycol, DBCO-PEG4-Acid

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Size/SKUAvailabilityPrice
5 mg
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$77.90
$58.42
50 mg
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$519.00
$389.25

About This Item

Empirical Formula (Hill Notation):
C32H40N2O8
Molecular Weight:
580.67
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:

$58.42

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Quality Segment

form

solid

reaction suitability

reaction type: click chemistry, reagent type: linker

functional group

carboxylic acid

storage temp.

−20°C

SMILES string

O=C(CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3

InChI

1S/C32H40N2O8/c35-30(33-16-18-40-20-22-42-24-23-41-21-19-39-17-15-32(37)38)11-5-6-12-31(36)34-25-28-9-2-1-7-26(28)13-14-27-8-3-4-10-29(27)34/h1-4,7-10H,5-6,11-12,15-25H2,(H,33,35)(H,37,38)

InChI key

RMYANOWYMFCGGS-UHFFFAOYSA-N

Application

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.
Dibenzocyclooctyne-PEG4-acid may be used as a substrate in azide-cyclooctyne cycloaddition reactions.

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This Item
761982764167760676
description

for Copper-free Click Chemistry

description

for Copper-free Click Chemistry

description

-

description

for Copper-free Click Chemistry

form

solid

form

solid

form

liquid

form

solid

functional group

carboxylic acid

functional group

hydroxyl

functional group

alkyne, carboxylic acid

functional group

maleimide

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

reaction suitability

reagent type: linker, reaction type: click chemistry

reaction suitability

reaction type: click chemistry, reagent type: linker

reaction suitability

reagent type: cross-linking reagent, reaction type: click chemistry

reaction suitability

reagent type: cross-linking reagent, reaction type: click chemistry

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

  1. Do you have non natural aminoacids for click labelling? We are looking for endo-BCN-L-Lysine or TCO*K

    1 answer
    1. Currently there is not an Endo-BNCL-Lysine product offered. See the link below for our reagents for Click Chemistry: https://www.sigmaaldrich.com/products/chemistry-and-biochemicals/chemical-biology/click-chemistry-reagents?country=US&language=en&cmsRoute=products&cmsRoute=chemistry-and-biochemicals&cmsRoute=chemical-biology&cmsRoute=click-chemistry-reagents&page=1ns.

      Should you be interested in a custom quote, please navigate to the link https://www.sigmaaldrich.com/support/customer-support, click on "Quotes" under the Orders Section with all the required information so that a member of Sales team can assist.

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