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768154

AdBrettPhos

95%, solid

Synonym(s):

Di-Ad-BrettPhos

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100 mg

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$154.00
500 mg

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$701.00
1 g
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$986.00

About This Item

Empirical Formula (Hill Notation):
C43H61O2P
CAS Number:
Molecular Weight:
640.92
MDL number:
UNSPSC Code:
12352112
PubChem Substance ID:
NACRES:
NA.22

$154.00


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Product Name

AdBrettPhos, 95%

Quality Segment

product line

Buchwald Ligand

assay

95%

form

solid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: ligand

mp

231-235 °C

functional group

phosphine

SMILES string

COc1ccc(OC)c(c1P(C23CC4CC(CC(C4)C2)C3)C56CC7CC(CC(C7)C5)C6)-c8c(cc(cc8C(C)C)C(C)C)C(C)C

InChI

1S/C43H61O2P/c1-25(2)34-17-35(26(3)4)39(36(18-34)27(5)6)40-37(44-7)9-10-38(45-8)41(40)46(42-19-28-11-29(20-42)13-30(12-28)21-42)43-22-31-14-32(23-43)16-33(15-31)24-43/h9-10,17-18,25-33H,11-16,19-24H2,1-8H3

InChI key

NMGHOZQCYNKWBG-UHFFFAOYSA-N

General description

AdBrettPhos is a phosphine-based ligand used in the direct monoarylation of ammonia and suppresses diarylation. In addition, it is a good ligand for five-membered heteroarene couplings and is employed in the preparation of phosphine-ligated palladium complexes to facilitate C-N coupling reactions.

Application

AdBrettPhos can be used as an effective ligand for synthesizing [(L·Pd)n ·(1,5-cyclooctadiene)] pre-catalyst that can be used for the Pd-catalyzed fluorination of aryl triflates.

AdBrettPhos has been used in the Palladium-Catalyzed C-O Cross-Coupling of Primary Alcohols.

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This Item
936839PMC2008CDS025458
description

95%

description

-

description

≥98%, ISOM8™

description

AldrichCPR

reaction suitability

reaction type: Negishi Coupling, reaction type: Stille Coupling, reaction type: Hiyama Coupling, reagent type: ligand, reaction type: Heck Reaction, reaction type: Sonogashira Coupling, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Suzuki-Miyaura Coupling

reaction suitability

reagent type: ligand

reaction suitability

reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reagent type: ligand, reaction type: Suzuki-Miyaura Coupling, reaction type: Hiyama Coupling, reaction type: Heck Reaction, reaction type: Negishi Coupling

reaction suitability

-

assay

95%

assay

-

assay

(HPLC), ≥98%

assay

-

form

solid

form

solid

form

solid

form

-

functional group

phosphine

functional group

-

functional group

phosphine

functional group

-

Quality Level

100

Quality Level

100

Quality Level

300

Quality Level

-

mp

231-235 °C

mp

-

mp

231-235 °C

mp

-


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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