901490
(S,R,S)-AHPC hydrochloride
≥97%
Synonym(s):
(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride, E3 Ligase ligand, Ligand for PROTAC® research, VH032
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
100 mg | Available to ship TODAYfromMILWAUKEE | $1,220.00 |
About This Item
ligand
VH032
Quality Segment
assay
≥97%
form
powder or crystals
reaction suitability
reagent type: ligand
technique(s)
targeted protein degradation: suitable
storage temp.
2-8°C
SMILES string
N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)C(C)(C)C.Cl
InChI key
JYRTWGCWUBURGU-MSSRUXLCSA-N
Application
Other Notes
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities
Modular PROTAC Design for the DegradationofOncogenic BCR-ABL
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4
Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)
Legal Information
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This Item | |||
|---|---|---|---|
| description ≥97% | description - | description - | description ≥95% |
| assay ≥97% | assay - | assay ≥95% | assay ≥95% |
| reaction suitability reagent type: ligand | reaction suitability reactivity: carboxyl reactive, reagent type: ligand-linker conjugate | reaction suitability reaction type: click chemistry, reagent type: ligand-linker conjugate | reaction suitability - |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| form powder or crystals | form solid | form powder | form powder or crystals |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| ligand VH032 | ligand VH032 | ligand VH032 | ligand VH032 |
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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