901503
(S,R,S)-AHPC-PEG1-Alkyne
≥95%
Synonym(s):
(2S,4R)-1-((S)-3,3-Dimethyl-2-(3-(prop-2-yn-1-yloxy)propanamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, CrosslinkerE3 Ligase ligand conjugate, Protein degrader building block for PROTAC® research, Template for synthesis of targeted protein degrader, VH032 conjugate
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| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Available to ship TODAYfromMILWAUKEE | $675.00 |
About This Item
ligand
VH032
Quality Segment
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry, reagent type: ligand-linker conjugate
technique(s)
targeted protein degradation: suitable
functional group
alkyne
storage temp.
2-8°C
SMILES string
O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H](C[C@@H](O)C3)N3C([C@H](C(C)(C)C)NC(CCOCC#C)=O)=O
InChI key
AFKRHNLUPSUNPJ-OTNCWRBYSA-N
Application
Automate your VHL-PEG based PROTACs with Synple Automated Synthesis Platform (SYNPLE-SC002)
Other Notes
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Targeted Protein Degradation by Small Molecules
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95% | description ≥95% | description ≥95% | description - |
| ligand VH032 | ligand VH032 | ligand VH032 | ligand VH032 |
| assay ≥95% | assay ≥95% | assay ≥95% | assay - |
| reaction suitability reagent type: ligand-linker conjugate, reaction type: click chemistry | reaction suitability reaction type: click chemistry, reagent type: ligand-linker conjugate | reaction suitability reagent type: ligand-linker conjugate, reaction type: click chemistry | reaction suitability reagent type: ligand-linker conjugate, reaction type: click chemistry |
| form powder or crystals | form powder | form powder or crystals | form powder |
| technique(s) targeted protein degradation: suitable | technique(s) targeted protein degradation: suitable | technique(s) targeted protein degradation: suitable | technique(s) targeted protein degradation: suitable |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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