904880
Pomalidomide-C6-PEG1-C3-PEG1-butyl azide
≥95%
Synonym(s):
Crosslinker−E3 ligase ligand conjugate, Pomalidomide-6-5-6-N3, 6-((5-((6-Azidohexyl)oxy)pentyl)oxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)hexanamide, Protein degrader building block for PROTAC® research, Template for synthesis of targeted protein degrader
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| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Check Cart for Availability | $1,090.00 |
About This Item
ligand
pomalidomide
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry, reagent type: ligand-linker conjugate
technique(s)
targeted protein degradation: suitable
functional group
azide
storage temp.
2-8°C
SMILES string
O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3NC(CCCCCOCCCCCOCCCCCCN=[N+]=[N-])=O)=O)NC1=O
InChI key
XTRFVWPKELKMMN-UHFFFAOYSA-N
Application
Other Notes
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Targeted Protein Degradation by Small Molecules
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95% | description ≥95% | description ≥95% | description ≥95% |
| form powder or crystals | form powder or crystals | form powder or crystals | form powder or crystals |
| functional group azide | functional group azide | functional group alkyl halide | functional group alkyl halide |
| assay ≥95% | assay ≥95% | assay ≥95% | assay ≥95% |
| technique(s) targeted protein degradation: suitable | technique(s) targeted protein degradation: suitable | technique(s) targeted protein degradation: suitable | technique(s) targeted protein degradation: suitable |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| reaction suitability reagent type: ligand-linker conjugate, reaction type: click chemistry | reaction suitability reagent type: ligand-linker conjugate, reaction type: click chemistry | reaction suitability reactivity: sulfuryl reactive, reagent type: ligand-linker conjugate | reaction suitability reagent type: ligand-linker conjugate, reactivity: sulfuryl reactive |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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