917818
(S,R,S)-AHPC-C9-NH2 hydrochloride
≥95%
Synonym(s):
(2S,4R)-1-((S)-2-(10-aminodecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride, Crosslinker−E3 Ligase ligand conjugate, Protein degrader building block for PROTAC® research, Template for synthesis of targeted protein degrader, VH032 conjugate
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Check Cart for Availability | $362.00 |
About This Item
ligand
VH032
Quality Segment
assay
≥95%
form
powder or crystals
reaction suitability
reactivity: carboxyl reactive, reagent type: ligand-linker conjugate
technique(s)
targeted protein degradation: suitable
functional group
amine
storage temp.
2-8°C
SMILES string
CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(CCCCCCCCCN)=O)C(C)(C)C)=O)=O)C=C2.Cl
InChI
1S/C32H49N5O4S.ClH/c1-22-28(42-21-35-22)24-15-13-23(14-16-24)19-34-30(40)26-18-25(38)20-37(26)31(41)29(32(2,3)4)36-27(39)12-10-8-6-5-7-9-11-17-33;/h13-16,21,25-26,29,38H,5-12,17-20,33H2,1-4H3,(H,34,40)(H,36,39);1H/t25-,26+,29-;/m1./s1
InChI key
CXWPAWUFEPOOLS-DDLJGEAHSA-N
Application
Other Notes
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Targeted Protein Degradation by Small Molecules
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95% | description - | description - | description ≥95% |
| reaction suitability reagent type: ligand-linker conjugate, reactivity: carboxyl reactive | reaction suitability reagent type: ligand-linker conjugate, reactivity: carboxyl reactive | reaction suitability reactivity: amine reactive, reagent type: ligand-linker conjugate | reaction suitability reagent type: ligand-linker conjugate, reactivity: carboxyl reactive |
| functional group amine | functional group amine | functional group carboxylic acid | functional group amine |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| form powder or crystals | form solid | form powder | form powder or crystals |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| assay ≥95% | assay - | assay ≥95% | assay ≥95% |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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