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| Size/SKU | Availability | Price |
|---|---|---|
10 g | Check Cart for Availability | $100.00 |
50 g | Check Cart for Availability | $325.00 |
About This Item
Linear Formula:
NCCO2C2H5
CAS Number:
Molecular Weight:
99.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-797-9
Beilstein/REAXYS Number:
635955
MDL number:
Assay:
≥95%
Form:
liquid
$100.00
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Quality Segment
assay
≥95%
form
liquid
refractive index
n20/D 1.381 (lit.)
bp
115-116 °C (lit.)
density
1.003 g/mL at 25 °C (lit.)
functional group
ester, nitrile
SMILES string
CCOC(=O)C#N
InChI
1S/C4H5NO2/c1-2-7-4(6)3-5/h2H2,1H3
InChI key
MSMGXWFHBSCQFB-UHFFFAOYSA-N
Application
Ethyl cyanoformate is a general cyanating agent. It can be used in the nucleophilic addition of cyanide to carbonyl compounds, oxidative cyanation of tertiary amines and in the synthesis of β-cyano-substituted acrylates from alkynes.
Ethyl cyanoformate can be used as a cyanide source for the cyanation of:
- Activated olefins in the presence of a titanium catalyst.
- Carbonyl compounds catalyzed by 4-dimethylaminopyridine (DMAP) to yield corresponding cyanohydrin carbonates under metal-free and solvent-free conditions.
- Aldehydes and 2,2,2-trifluoroacetophenone catalyzed by N-heterocyclic carbene (NHC) to yield corresponding cyanohydrins ethyl carbonates.
1 of 1
This Item | |
|---|---|
| description ≥95% | description 99% |
| assay ≥95% | assay 99% |
| Quality Level 100 | Quality Level 100 |
| bp 115-116 °C (lit.) | bp 100-101 °C (lit.) |
| density 1.003 g/mL at 25 °C (lit.) | density 1.072 g/mL at 25 °C (lit.) |
| refractive index n20/D 1.381 (lit.) | refractive index n20/D 1.374 (lit.) |
| form liquid | form liquid |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
Storage Class
3 - Flammable liquids
WGK
WGK 3
Flash Point (°F)
75.2 °F - closed cup
Flash Point (°C)
24 °C - closed cup
PPE (personal protective equipment)
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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