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E18859

Ethyl cyanoformate

≥95%

Synonym(s):

2-Ethoxy-2-oxoacetonitrile, Cyanocarbonyloxyethane, Cyanoformic acid ethyl ester, Ethoxycarbonyl cyanide, Ethyl carbonocyanidate

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Size/SKUAvailabilityPrice
10 g
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$100.00
50 g
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$325.00

About This Item

Linear Formula:
NCCO2C2H5
CAS Number:
Molecular Weight:
99.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-797-9
Beilstein/REAXYS Number:
635955
MDL number:
Assay:
≥95%
Form:
liquid

$100.00


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Quality Segment

assay

≥95%

form

liquid

refractive index

n20/D 1.381 (lit.)

bp

115-116 °C (lit.)

density

1.003 g/mL at 25 °C (lit.)

functional group

ester, nitrile

SMILES string

CCOC(=O)C#N

InChI

1S/C4H5NO2/c1-2-7-4(6)3-5/h2H2,1H3

InChI key

MSMGXWFHBSCQFB-UHFFFAOYSA-N

Application

Ethyl cyanoformate is a general cyanating agent. It can be used in the nucleophilic addition of cyanide to carbonyl compounds, oxidative cyanation of tertiary amines and in the synthesis of β-cyano-substituted acrylates from alkynes.
Ethyl cyanoformate can be used as a cyanide source for the cyanation of:
  • Activated olefins in the presence of a titanium catalyst.
  • Carbonyl compounds catalyzed by 4-dimethylaminopyridine (DMAP) to yield corresponding cyanohydrin carbonates under metal-free and solvent-free conditions.
  • Aldehydes and 2,2,2-trifluoroacetophenone catalyzed by N-heterocyclic carbene (NHC) to yield corresponding cyanohydrins ethyl carbonates.


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This Item
319813
description

≥95%

description

99%

assay

≥95%

assay

99%

Quality Level

100

Quality Level

100

bp

115-116 °C (lit.)

bp

100-101 °C (lit.)

density

1.003 g/mL at 25 °C (lit.)

density

1.072 g/mL at 25 °C (lit.)

refractive index

n20/D 1.381 (lit.)

refractive index

n20/D 1.374 (lit.)

form

liquid

form

liquid


Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Codes

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

WGK

WGK 3

Flash Point (°F)

75.2 °F - closed cup

Flash Point (°C)

24 °C - closed cup

PPE (personal protective equipment)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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