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F6562

Fmoc-(R)-2-(7-octenyl)Ala-OH

for peptide synthesis

Synonym(s):

(R)-N-Fmoc-α-(7-Octenyl)alanine, Fmoc-(R)-2-(7-octenyl)alanine, Fmoc-(R)-2-amino-2-methyl-dec-6-enoic acid

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Size/SKUAvailabilityPrice
1 g
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$719.00
5 g
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$1,730.00

About This Item

Empirical Formula (Hill Notation):
C26H31NO4
CAS Number:
Molecular Weight:
421.53
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:

$719.00


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Product Name

Fmoc-(R)-2-(7-octenyl)Ala-OH,

form

solid

Quality Segment

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

−20°C

SMILES string

O=C(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)N[C@@](CCCCCCC=C)(C)C(O)=O

InChI

1S/C26H31NO4/c1-3-4-5-6-7-12-17-26(2,24(28)29)27-25(30)31-18-23-21-15-10-8-13-19(21)20-14-9-11-16-22(20)23/h3,8-11,13-16,23H,1,4-7,12,17-18H2,2H3,(H,27,30)(H,28,29)/t26-/m1/s1

InChI key

MADFVGMQNXRFAF-AREMUKBSSA-N

Application

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

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This Item
F6687F6312F6187
description

-

description

≥97%

description

≥97%

description

≥97%

form

solid

form

solid

form

solid

form

solid

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

200

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis


Pictograms

Environment

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Aquatic Acute 1

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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