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Methotrexate-D₃ solution

Name: Methotrexate-D<SUB>3</SUB> solution
Brand: CERILLIAN
Price: 247 USD
Availability: InStock

100 μg/mL in methanol with 0.01N NaOH, ampule of 1 mL, certified reference material, Cerilliant^®

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1 mL	Check Cart for Availability	$247.00

About This Item

Empirical Formula (Hill Notation):

C₂₀H₁₉N₈O₅D₃

CAS Number:

432545-63-6

Molecular Weight:

457.46

NACRES:

NA.24

UNSPSC Code:

41116107

EC Number:

200-659-6

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Properties

grade

certified reference material

Quality Segment

300

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

100 μg/mL in methanol with 0.01N NaOH

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

[2H]C([2H])([2H])N(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O

InChI

1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/i1D3

InChI key

FBOZXECLQNJBKD-FIBGUPNXSA-N

Description

General description

An internal standard suitable for therapeutic drug monitoring analyses of methotrexate patient serum samples by LC-MS/MS. Used in the treatment of cancer and autoimmune diseases, methotrexate is an antimetabolite and antifolate drug monitored by clinical labs to ensure patients remain within the drug′s therapeutic range. The Snap-N-Spike^® solution format allows laboratories to eliminate weighing operations of hazardous substances such as methotrexate, significantly reducing occupational exposure hazards related to handling of acutely toxic powders, and provides the ability to spike into their matrix of choice just before use.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

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This Item	M136	M137	M202
Supelco M153 Methotrexate-D₃ solution	Supelco M136 Methotrexate solution	Supelco M137 Mycophenolic acid-d₃ solution	Supelco M202 Methocarbamol-D₃ solution
description 100 μg/mL in methanol with 0.01N NaOH, ampule of 1 mL, certified reference material, Cerilliant^®	description 1.0 mg/mL in methanol with 0.1N NaOH, ampule of 1 mL, certified reference material, Cerilliant^®	description 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®	description 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant^®
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) clinical testing	application(s) clinical testing
technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable
form liquid	form liquid	form liquid	form liquid
Quality Level 300	Quality Level 300	Quality Level 300	Quality Level 300
grade certified reference material	grade certified reference material	grade certified reference material	grade certified reference material
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

pictograms

GHS02,GHS06,GHS08,GHS05

signalword

Danger

hcodes

H225,H290,H301 + H311 + H331,H370

pcodes

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Met. Corr. 1 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

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