Key Documents

Anti-CAPZIP Antibody

Name: Anti-CAPZIP Antibody
Brand: MM
Price: 441 USD
Availability: InStock

from rabbit, purified by affinity chromatography

Synonym(s):

RCSD domain containing 1, capZ-interacting protein, Protein kinase substrate CapZIP, protein kinase substrate MK2S4, RCSD domain-containing protein 1

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100 μL	Check Cart for Availability	$441.00

About This Item

eCl@ss:

32160702

UNSPSC Code:

12352203

NACRES:

NA.84

Clone:

polyclonal

Species reactivity:

human

Application:

IP, WB

Citations:

$441.00

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Properties

biological source

rabbit

Quality Segment

100

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

NP_443094

UniProt accession no.

Q6JBY9

shipped in

wet ice

Gene Information

human ... RCSD1(92241)

Description

General description

CAPZIP (CapZ-interacting protein) is highly expressed in immune cells and muscle and uniquely interacts with CapZ, an F-actin capping protein, in splenocytes. Phosphorylation of CAPZIP is thought to regulate CapZ ability to remodel actin filament assembly. CAPZIP may also contain a CPI (capping protein interaction) motif that seems to restrict capping protein to a low-affinity, filament-binding conformation.

~70 kDa observed. The native form of CAPZIP runs anomalously, with a molecular mass of 70 kDa (much slower than its real molecular mass). The 47 kDa band may be non-specific, a splice variant or a degradation product. (Eyers, C.E., et al. (2005). Biochem J. 389(1):127-135.). An uncharacterized band appears at ~18 kDa

Immunogen

GST-tagged recombinant protein corresponding to human CAPZIP.

Application

Anti-CAPZIP detects levels of CAPZIP proteins & has been published & validated for use in WB & IP.

Immunoprecipitation Analysis: 10 µg from a previous lot immunoprecipitated CAPZIP from Jurkat cell lysate.

Other homologies: Mouse (64% sequence homology). Rat (58% sequence homology).

Research Category
Signaling

Research Sub Category
Cytoskeletal Signaling

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Jurkat cell lysate

Evaluated by Western Blot in Jurkat cell lysate.

Western Blot Analysis: 1:250 dilution of this antibody detected CAPZIP on 10 µg of Jurkat cell lysate.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

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This Item	AB6016	ABC346	ABS222
Sigma-Aldrich 072189 Anti-CAPZIP Antibody	Sigma-Aldrich AB6016 Anti-F-actin-capping protein subunit alpha-1 Antibody	Sigma-Aldrich ABC346 Anti-FAF1 Antibody	Sigma-Aldrich ABS222 Anti-DEPTOR Antibody
description from rabbit, purified by affinity chromatography	description from rabbit, purified by affinity chromatography	description from rabbit, purified by affinity chromatography	description from rabbit, purified by affinity chromatography
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
species reactivity human	species reactivity pig, mouse, human, rat	species reactivity rat, human	species reactivity human
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
UniProt accession no. Q6JBY9	UniProt accession no. P52907	UniProt accession no. Q9UNN5	UniProt accession no. Q8TB45
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
technique(s) immunoprecipitation (IP): suitable, western blot: suitable	technique(s) immunocytochemistry: suitable, western blot: suitable	technique(s) immunohistochemistry: suitable, western blot: suitable	technique(s) western blot: suitable

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Key Documents

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Anti-CAPZIP Antibody

from rabbit, purified by affinity chromatography

Select a Size

About This Item

$441.00

biological source

Quality Segment

antibody product type

clone

purified by

species reactivity

technique(s)

NCBI accession no.

UniProt accession no.

shipped in

Gene Information

General description

Immunogen

Application

Physical form

Preparation Note

Analysis Note

Disclaimer

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This Item

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Anti-CAPZIP Antibody

from rabbit, purified by affinity chromatography

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About This Item

07-2189

$441.00

biological source

Quality Segment

antibody product type

clone

purified by

species reactivity

technique(s)

NCBI accession no.

UniProt accession no.

shipped in

Gene Information

General description

Immunogen

Application

Physical form

Preparation Note

Analysis Note

Disclaimer

Compare Similar Items

This Item

Still not finding the right product?

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

Documentation

Certificates of Analysis (COA)

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