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239785

Cyclophosphamide Monohydrate

≥98% (HPLC), solid, anti-neoplastic agent, Calbiochem®

Synonym(s):

Cyclophosphamide Monohydrate, N,N- bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA, N,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA

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Size/SKUAvailabilityPrice
1 g
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$122.00

About This Item

Empirical Formula (Hill Notation):
C7H15Cl2N2O2P · xH2O
CAS Number:
6055-19-2
Molecular Weight:
261.09 (anhydrous basis)
UNSPSC Code:
51112507
NACRES:
NA.77
MDL number:
MFCD00149395
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze

$122.00

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Product Name

Cyclophosphamide Monohydrate, A widely used anti-neoplastic agent that also displays immunosuppressant properties.

Quality Segment

description

Merck USA index - 14, 747

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 30 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[P]1(=O)(NCCCO1)N(CCCl)CCCl.O

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI key

PWOQRKCAHTVFLB-UHFFFAOYSA-N

General description

A widely used anti-neoplastic agent that also displays immunosuppressant properties. Induces apoptotic cell death in rat thymus through the Fas/Fas ligand pathway.
A widely used antineoplastic agent that also displays immuno-suppressant activity. Induces apoptotic cell death in rat thymus throught Fas/Fas ligand pathway.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Fas/Fas ligand pathway
Product does not compete with ATP.
Reversible: no

Preparation Note

Solutions should be prepared fresh on the day of use.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Wang, G.J., and Cai, L. 1999. Mutat. Res.427, 125.
Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

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This Item
C0768PHR1404444200
Cyclophosphamide Monohydrate A widely used anti-neoplastic agent that also displays immunosuppressant properties.

Sigma-Aldrich

239785

Cyclophosphamide Monohydrate

Cyclophosphamide monohydrate bulk package

Sigma-Aldrich

C0768

Cyclophosphamide monohydrate

Cyclophosphamide Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1404

Cyclophosphamide

MDL-12,330A, Hydrochloride Cell-permeable and irreversible inhibitor of adenylate cyclase (IC50 = 250 µM).

Sigma-Aldrich

444200

MDL-12,330A, Hydrochloride

description

A widely used anti-neoplastic agent that also displays immunosuppressant properties.

description

bulk package

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

Cell-permeable and irreversible inhibitor of adenylate cyclase (IC50 = 250 µM).

form

solid

form

powder

form

-

form

solid

assay

≥98% (HPLC)

assay

97.0-103.0% (HPLC)

assay

-

assay

≥98% (HPLC)

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

water: 30 mg/mL

solubility

-

solubility

-

solubility

water: 3 mg/mL, DMSO: 10 mg/mL, ethanol: 5 mg/mL

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

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