474790
MG-132
≥98% (HPLC), proteasome inhibitor, solid
Synonym(s):
Z-Leu-Leu-Leu-al, Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, Z-LLL-CHO, Proteasome Inhibitor XI, MG-132
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Check Cart for Availability | $61.90 |
5 mg | Check Cart for Availability | $184.00 |
10 mg | Check Cart for Availability | $253.00 |
20 mg | Check Cart for Availability | $430.00 |
About This Item
$61.90
Product Name
MG-132, A cell-permeable, potent, reversible proteasome inhibitor (Ki = 4 nM).
Quality Segment
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 20 mg/mL, ethanol: 20 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
[H]C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
InChI
1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1
InChI key
TZYWCYJVHRLUCT-VABKMULXSA-N
General description
Biochem/physiol Actions
proteasome
Preparation Note
Other Notes
Steinhilb, M.L., et al. 2001. J. Biol. Chem.276, 4476.
Meriin, A.B., et al. 1998. J. Biol. Chem. 273, 6373.
Adams, J., and Stein, R. 1996. Ann. Rep. Med. Chem.31, 279.
Klafki, H.W., et al. 1996. J. Biol. Chem.271, 2865.
Lee, D.H., and Goldberg, A.L., 1996. J. Biol. Chem.271, 27280.
Wiertz, E.J., et al. 1996. Cell84, 769.
Jensen, T.J., et al. 1995. Cell 83, 129.
Read, M.A., et al. 1995. Immunity2, 493.
Rock, K.L., et al. 1994. Cell 78, 761.
Legal Information
Disclaimer
1 of 1
This Item | |||
|---|---|---|---|
| description A cell-permeable, potent, reversible proteasome inhibitor (Ki = 4 nM). | description InSolution, ≥98%, 10 mM, reversible proteasome inhibitor | description ≥90% (HPLC) | description Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). |
| form solid | form liquid | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥90% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename Calbiochem® |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility ethanol: 20 mg/mL, DMSO: 20 mg/mL | solubility - | solubility DMSO: soluble | solubility ethanol: 25 mg/mL, DMSO: 25 mg/mL |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
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