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THP

Name: THP
Brand: MM
Price: 135 USD
Availability: InStock

A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT.

Synonym(s):

THP, Tris(hydroxypropyl)phosphine

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Size/SKU	Availability	Price
1 g	Check Cart for Availability	$135.00

About This Item

Empirical Formula (Hill Notation):

C₉H₂₁O₃P

CAS Number:

4706-17-6

Molecular Weight:

208.24

UNSPSC Code:

12352128

NACRES:

NA.25

MDL number:

MFCD00269835

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Properties

Quality Segment

100

assay

≥80% (³¹P-NMR)

form

viscous liquid

reaction suitability

reagent type: reductant

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated, protect from light

color

colorless

solubility

water: 20 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

P(CCCO)(CCCO)CCCO

InChI

1S/C9H21O3P/c10-4-1-7-13(8-2-5-11)9-3-6-12/h10-12H,1-9H2

InChI key

YICAEXQYKBMDNH-UHFFFAOYSA-N

Description

General description

A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT. THP is comparable with TCEP (Cat. No. 580560) as a reducing agent. Its reduction capacity against oxidized glutathione is 0.232 meq/g (Note: TCEP has a reduction capacity of 0.182 meq/g). THP is also more resistant to air oxidation as compared to DTT.

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Corrosive (L)

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This Item	71194M	646547	68957
Millipore 598250 THP	Millipore 71194M 0.5 M THP Solution	Supelco 646547 Tris(2-carboxyethyl)phosphine hydrochloride solution	Sigma-Aldrich 68957 Tris(2-carboxyethyl)phosphine hydrochloride
description A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT.	description Reducing agent compatible with His•Bind chromatography	description 0.5 M, pH 7.0(aqueous solution; pH was adjusted with ammonium hydroxide)	description BioUltra, suitable for electrophoresis, SDS-PAGE tested
assay ≥80% (³¹P-NMR)	assay -	assay -	assay 97.5-102.5%
Quality Level 100	Quality Level 400	Quality Level 200	Quality Level 100
form viscous liquid	form solution	form -	form powder
solubility water: 20 mg/mL	solubility -	solubility -	solubility H₂O: soluble
storage temp. 2-8°C	storage temp. −20°C	storage temp. -	storage temp. -
manufacturer/tradename Calbiochem^®	manufacturer/tradename Novagen^®	manufacturer/tradename -	manufacturer/tradename -

signalword

Danger

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

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