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8.02301
1,1′-Carbonyldiimidazole
Greener Alternative
for synthesis
Synonym(s):
1,1′-Carbonyldiimidazole
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
2 g | Estimated to ship onSeptember 02, 2026 | $36.00 |
5 g | Estimated to ship onSeptember 02, 2026 | $38.00 |
25 g | Estimated to ship onSeptember 02, 2026 | $138.00 |
100 g | Estimated to ship onSeptember 02, 2026 | $423.00 |
2.5 kg | Estimated to ship onAugust 17, 2026. | $900.00 |
About This Item
Quality Segment
assay
≥97.0% (GC)
form
powder
potency
1071 mg/kg LD50, oral (Rat)
reaction suitability
reaction type: Carbonylations
greener alternative product characteristics
Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
pH
7.7 (20 °C, 50 g/L in H2O)
mp
116-120 °C
application(s)
peptide synthesis
greener alternative category
storage temp.
2-8°C
SMILES string
[n]2(cncc2)C(=O)[n]1cncc1
InChI
1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H
InChI key
PFKFTWBEEFSNDU-UHFFFAOYSA-N
General description
Application
- Facile Synthesis of 2-(1H-indol-3-yl)-acetamides: Synthesizing acetamides using 1,1′-Carbonyldiimidazole, showcasing its role in forming a reactive intermediate with pyridine (KMK Kanwal, B Fatima, B Bano, U Salar - J. Chem. Soc. Pak, 2016).
- Nanoflower Enhanced Capacitive Aptasensor: The synthesis of a novel hybrid nanoflower using 1,1′-Carbonyldiimidazole for attomolar detection limits in milk contamination detection (IG Subramani, V Perumal, SCB Gopinath - Scientific Reports, 2021).
- Thermodynamic Properties Analysis: The data on the thermodynamic properties of 1,1′-Carbonyldiimidazole and its applications in understanding material behaviors (JB Campos, JM Toro Jauregui - Journal of the Mexican Chemical Society, 2020).
- Synthesis of Deuterated Triacylglycerides: The use of 1,1′-Carbonyldiimidazole in the synthesis of medium chain triglyceride oil, highlighting its application in food emulsion studies (K Schwärzer, T Heiden‐Hecht, Y Chen - European Journal of Organic Chemistry, 2023).
- Mechanochemical Carbamate Synthesis: The use of 1,1′-Carbonyldiimidazole in an eco-friendly synthesis of carbamates, demonstrating its versatility as an acyl transfer reagent (M Lanzillotto, L Konnert, F Lamaty - ACS Sustainable Chemistry & Engineering, 2015).
Analysis Note
Melting range (lower value): ≥ 115 °C
Melting range (upper value): ≤ 121 °C
Identity (IR): passes test
1 of 1
This Item | |||
|---|---|---|---|
| description for synthesis | description reagent grade | description ≥97.0% (T) | description BCR®, certified reference material |
| assay ≥97.0% (GC) | assay ≥90.0% (proton, NMR) | assay ≥97.0% (T) | assay - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level - |
| reaction suitability reaction type: Carbonylations | reaction suitability reaction type: Carbonylations | reaction suitability reaction type: Carbonylations | reaction suitability - |
| mp 116-120 °C | mp 117-122 °C (lit.) | mp 115-122 °C, 117-122 °C (lit.) | mp - |
| form powder | form solid | form solid | form - |
| storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C | storage temp. 2-8°C |
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C
flash_point_f
Not applicable
flash_point_c
Not applicable
hcodes
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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