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8.08154

Thionyl chloride

for synthesis

Synonym(s):

Thionyl chloride, Sulfurous acid dichloride, Sulfurous oxychloride

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Size/SKUAvailabilityPrice
500 mL
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$113.00
1 L
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$188.00
2.5 L
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$371.00

About This Item

Linear Formula:
SOCl2
CAS Number:
Molecular Weight:
118.97
UNSPSC Code:
12352307
EC Index Number:
231-748-8
NACRES:
NA.22
MDL number:
Grade:
synthesis grade
Form:
liquid

$113.00


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grade

synthesis grade

Quality Segment

vapor pressure

121 hPa ( 20 °C)

form

liquid

potency

324 mg/kg LD50, oral (Rat)

bp

76 °C/1013 hPa

mp

-104.5 °C

density

1.64 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

[S](=O)(Cl)Cl

InChI

1S/Cl2OS/c1-4(2)3

InChI key

FYSNRJHAOHDILO-UHFFFAOYSA-N

General description

Thionyl chloride is an inorganic acid chloride. It is mainly used as a chlorinating agent in organic synthesis for the production of organochlorine compounds.

Application

Thionyl chloride can be used as a catalyst to synthesize:
  • 4-(sulfinylamino)-1,2,4-triazole by reacting with 4-amino-1,2,4-triazole.
  • Isothiazolopyrimidines from aminouracils via cyclization reaction.
  • 1,2,6-triazine S-oxides by reacting with diimines via condensation reactions in the presence of pyridine.
  • 2-oxo-1,3,2-dioxathianes by condensation reaction with alkane-1,3-diols.
  • Cyclic sulfites by reacting with nitroglycols.
  • Microporous organic polymers by aldol self-condensation reaction of di and multiacetyl building blocks.

Analysis Note

Assay (argentometric): ≥ 99.0 %
Identity (IR): passes test

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This Item
320536230464447285
description

for synthesis

description

reagent grade, 97%

description

ReagentPlus®, ≥99%

description

ReagentPlus®, 99.5%, low iron

form

liquid

form

liquid

form

liquid

form

liquid

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

grade

synthesis grade

grade

reagent grade

grade

-

grade

-

vapor pressure

121 hPa ( 20 °C)

vapor pressure

97 mmHg ( 20 °C)

vapor pressure

97 mmHg ( 20 °C)

vapor pressure

97 mmHg ( 20 °C)

mp

-104.5 °C

mp

−105 °C (lit.)

mp

−105 °C (lit.)

mp

−105 °C (lit.)

density

1.64 g/cm3 at 20 °C

density

1.631 g/mL at 25 °C (lit.)

density

1.631 g/mL at 25 °C (lit.)

density

1.631 g/mL at 25 °C (lit.)


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pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

target_organs

Respiratory system

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

supp_hazards

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Do any of the Thionyl chlorides come under a SureSeal? If so, could I get the exact product #? I accidentally bought an ampule last time which was useless for my purposes.

    1 answer
    1. This product is packaged in glass bottles with a screw cap. See the links below to review products that are packaged with the Sure/Seal system:

      230464
      https://www.sigmaaldrich.com/product/sial/230464

      320536
      https://www.sigmaaldrich.com/product/sial/320536

      Helpful?

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