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8.18759

Tetra-n-butylammonium hydroxide

(20% solution in water) for synthesis

Synonym(s):

N,N,N-Tributyl-1-butanaminium hydroxide, TBAH, Tetrabutylammonium hydroxide

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Size/SKUAvailabilityPrice
50 mL
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$43.50
100 mL
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$78.60
500 mL
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$260.00

About This Item

NACRES:
NA.22
UNSPSC Code:
12352107
Form:
liquid

$43.50


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Quality Segment

form

liquid

reaction suitability

core: ammonium, reaction type: phase-transfer

pH

14 (20 °C in H2O)

bp

102 °C/1013 hPa

density

0.99 g/cm3 at 20 °C

storage temp.

2-30°C

Application


  • Hydration structures of lactic acid: Research explored the hydration structures of lactic acid and characterized the ionic clathrate hydrate formed with a biological organic acid anion, utilizing Tetra-n-butylammonium hydroxide in this process (Muromachi et al., 2014).

  • Protection of ribonucleosides in RNA synthesis: A study demonstrated the use of Tetra-n-butylammonium hydroxide in the solid-phase synthesis of RNA sequences, particularly for the protection of 2′-hydroxyl groups of ribonucleosides (Cieslak et al., 2013).

  • Analysis of cosmetic products: Tetra-n-butylammonium hydroxide is used as a ion-pairing agent in the simultaneous analysis of various organic acids in cosmetic products by enhancing the extraction efficiency during high-performance liquid chromatography (Mikami et al., 2002).

  • Determination of calcium dobesilate in human plasma: The compound was employed in the ion-pairing extraction and high-performance liquid chromatography for the determination of calcium dobesilate in human plasma, highlighting its utility in clinical analytical methods (Rona and Ary, 2001).

Analysis Note

Assay (acidimetric): 18.0 - 22.0 %
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.


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Signal Word

Danger

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Pictograms

Corrosion

Hazard Codes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials



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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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