This product has not been tested for use in cell culture. The end user would have to determine suitability. However, product N3876, while not tested for cell culture applications, has been used successfully by other researchers.
Please see the link below to review this product option:
https://www.sigmaaldrich.com/product/sigma/n3876
8.20877
(-)-Nicotine
for synthesis
Synonym(s):
(-)-Nicotine, 3-(1-Methyl-2-pyrrolidinyl)pyridine, (S)-(-)-Nicotine
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| Size/SKU | Availability | Price |
|---|---|---|
25 mL | Estimated to ship onSeptember 07, 2026 | $72.40 |
100 mL | Estimated to ship onSeptember 07, 2026 | $173.00 |
1 L | Estimated to ship onSeptember 23, 2026 | $1,560.00 |
About This Item
Empirical Formula (Hill Notation):
C10H14N2
CAS Number:
Molecular Weight:
162.23
UNSPSC Code:
12352005
EC Index Number:
200-193-3
NACRES:
NA.22
MDL number:
Assay:
≥99.0% (GC)
Form:
liquid
vapor pressure
0.06 hPa ( 20 °C)
Quality Segment
assay
≥99.0% (GC)
form
liquid
autoignition temp.
240 °C
potency
50 mg/kg LD50, oral (Rat), 50 mg/kg LD50, skin (Rabbit)
expl. lim.
0.7-4 % (v/v)
pH
10.2 (20 °C, 8.1 g/L in H2O)
bp
248.8 °C/1013 hPa
mp
-79 °C
transition temp
flash point 111 °C
density
1.01 g/cm3 at 20 °C
storage temp.
2-30°C
SMILES string
N1([C@@H](CCC1)c2cnccc2)C
InChI
1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
InChI key
SNICXCGAKADSCV-JTQLQIEISA-N
Analysis Note
Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.009 - 1.012
Enantiomeric purity: ≥ 99.0 % (a/a)
Identity (IR): passes test
Density (d 20 °C/ 4 °C): 1.009 - 1.012
Enantiomeric purity: ≥ 99.0 % (a/a)
Identity (IR): passes test
signalword
Danger
Hazard Classifications
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
wgk
WGK 3
flash_point_f
213.8 °F - closed cup
flash_point_c
101 °C - closed cup
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
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Can i use this on A549 cell line for COPD research ? It is applicable for cell culture research.
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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This is pure nicotine solution, right? This is not nicotine that has been dissolved in a solvent.
1 answer-
Yes, this product is a neat or pure form of Nicotine. Based on a density of 1.02 g/ml and a molecular weight of 162.2 g/mole, this neat liquid has a calculated molar concentration of 6.3 M.
Helpful?
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What is the concentration in the 25ml bottle preferably in mg/ml
1 answer-
This product is a neat liquid with a minimum purity of 99%. The density is 1.01 g/mL and the molecular weight is 162.23. The calculated concentration of this product is approximately 6.2 M. This value will change slightly when considering the lot specific purity. This product is not tested for moisture content.
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