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8.52113

Fmoc-Asp(biotinyl-PEG)-OH

Novabiochem®

Synonym(s):

Fmoc-Asp(biotinyl-PEG)-OH, N-α-Fmoc-N-γ-(N-biotinyl-3-(2-(2-(3-aminopropyloxy)-ethoxy)-ethoxy)-propyl)-L-asparagine

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Size/SKUAvailabilityPrice
500 mg

Estimated to ship onOctober 15, 2026fromSAINT LOUIS

$481.00
1 g

Estimated to ship onSeptember 16, 2026fromSAINT LOUIS

$865.00

About This Item

Empirical Formula (Hill Notation):
C39H53N5O10S
Molecular Weight:
783.93
NACRES:
NA.22
UNSPSC Code:
12352209

$481.00

Estimated to ship onOctober 15, 2026Details

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Quality Segment

200

product line

Novabiochem®

assay

≥95.0% (HPLC), ≥98% (TLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

biotin

storage temp.

2-8°C

General description

In contrast to Fmoc-Lys(biotin)-OH, this novel biotin-labeled amino acid has excellent solubility in DMF and other solvents used in Fmoc SPPS [1]. The PEG-spacer restricts hindrance between the peptide and avidin, leading to better biotin binding. Furthermore, the hydrophilic nature of the PEG minimizes non-specific interactions that can arise from the spacer group becoming buried in the hydrophobic pocket of proteins.

Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis

Literature references

[1] B. Baumeister, et al. (2003) Biopolymers, 71, 339.

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1279

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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Fmoc-Asp(biotinyl-PEG)-OH Novabiochem®

Sigma-Aldrich

852113

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Sigma-Aldrich

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Fmoc-Glu(biotinyl-PEG)-OH

N-Biotinyl-NH(PEG)11-COOH Novabiochem®

Sigma-Aldrich

852340

N-Biotinyl-NH(PEG)11-COOH

N-Biotinyl-NH-(PEG)2-COOH . DIPEA (20 atoms) Novabiochem®

Sigma-Aldrich

851029

N-Biotinyl-NH-(PEG)2-COOH . DIPEA (20 atoms)

description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

form

powder

form

powder

form

powder

form

powder

assay

≥95.0% (HPLC), ≥98% (TLC)

assay

≥95.0% (HPLC), ≥97% (TLC)

assay

≥98% (TLC)

assay

≥95.0% (HPLC), ≥98% (TLC)

functional group

biotin

functional group

biotin

functional group

-

functional group

-

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

15-25°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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