8.52127
Fmoc-Glu(OtBu)-OPfp
Novabiochem®
Synonym(s):
Fmoc-Glu(OtBu)-OPfp, N-α-Fmoc-L-glutamic acid γ-t.-butyl ester pentafluorophenyl ester
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About This Item
Empirical Formula (Hill Notation):
C30H26F5NO6
CAS Number:
Molecular Weight:
591.52
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
Pricing and availability is not currently available.
Quality Segment
product line
Novabiochem®
assay
≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
mp
115-125 °C
application(s)
peptide synthesis
functional group
carboxylic acid
storage temp.
15-25°C
SMILES string
Fc1c(c(c(c(c1F)F)OC(=O)[C@@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)CCC(=O)OC(C)(C)C)F)F
InChI
1S/C30H26F5NO6/c1-30(2,3)42-21(37)13-12-20(28(38)41-27-25(34)23(32)22(31)24(33)26(27)35)36-29(39)40-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,36,39)/t20-/m0/s1
InChI key
AIDYQYOPUBOMTR-FQEVSTJZSA-N
General description
Pre-formed pentafluorophenyl ester for coupling of glutamic acid amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -20.5 - -15.5 °
Purity (TLC (0004)): <2% DCU
Assay (HPLC, area%): ≥ 98.0% (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -20.5 - -15.5 °
Purity (TLC (0004)): <2% DCU
Assay (HPLC, area%): ≥ 98.0% (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Replaces: 04-12-1506
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Skin Irrit. 2
Storage Class
11 - Combustible Solids
WGK
WGK 3
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