This particle is considered to be non-porous. The beads act as a separate gel phase rather than as a porous solid.
8.55014
NovaSyn®TG amino resin (130 µm)
Novabiochem®
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 g | Please contact Customer Service for Availability | $103.00 | |
| 5 g | Please contact Customer Service for Availability | $417.00 | |
| 25 g | Please contact Customer Service for Availability | $1,650.00 |
About This Item
NACRES:
NA.22
UNSPSC Code:
13111023
Quality Level
product line
NovaSyn® TG, Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
2-30°C
General description
NovaSyn TG amino resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol [1,2,3], in which the PEG chains have been terminally functionalized with an amino group. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis. This resin can be easily converted into other supports suitable for use in SPOS by acylation with the appropriate carboxylic acid-containing linker. For example, Hutchins and Chapman [4] have coupled Riniker′s HMPB linker to this resin and used it to prepare a range of ureas derived from glutamic acid.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30,113.
[4] S. M. Hutchins & K. T. Chapman (1994) Tetrahedron Lett., 35, 4055.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30,113.
[4] S. M. Hutchins & K. T. Chapman (1994) Tetrahedron Lett., 35, 4055.
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
This resin is a composite of low-crossed linked polystyrene and 3000-4000 M.W. polyethylene glycol, which has been terminally amino functionalised. 130µm beads.
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
This resin is a composite of low-crossed linked polystyrene and 3000-4000 M.W. polyethylene glycol, which has been terminally amino functionalised. 130µm beads.
Other Notes
Replaces: 01-64-0094
Legal Information
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
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This Item | |||
|---|---|---|---|
| reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis |
| product line NovaSyn® TG, Novabiochem® | product line NovaSyn® TG, Novabiochem® | product line NovaSyn® TG, Novabiochem® | product line NovaSyn® TG, Novabiochem® |
| functional group amine | functional group amine | functional group - | functional group alcohol |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| application(s) peptide synthesis | application(s) peptide synthesis | application(s) peptide synthesis | application(s) peptide synthesis |
| storage temp. 2-30°C | storage temp. 2-30°C | storage temp. 2-8°C | storage temp. 2-30°C |
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Novabiochem® offers polymer supports for solid phase peptide synthesis, suitable for various peptide lengths and sequences.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 8550140100 | 04027269678760 |
| 8550140005 | 04027269109752 |
| 8550140001 | 04027269109745 |
| 8550140025 | 04027269109769 |
| 8550141000 | 04027269678777 |
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Hello, are these particles porous or nonporous? Thank you
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