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8.55101

REM resin (50-100 mesh)

Novabiochem®

Synonym(s):

Acryloyl Wang resin

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Size/SKUAvailabilityPrice
1 g
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$83.70

About This Item

NACRES:
NA.22
UNSPSC Code:
13111023

$83.70


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Quality Segment

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis, reactivity: amine reactive

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

2-30°C

General description

Novabiochem® 50-100 mesh REM resin [1] is an exceptionally high quality resin, designed specially for use in IRORI Kans and other parallel synthesis applications that require supports with reproducible substitution and swelling properties containing minimal leachable impurities. This material is derived from poly(chloromethylstyrene-styrene-divinylbenzene) manufactured to ISO 9001 standards. Unlike other Merrifield supports, which are prepared by chloromethylation of polystyrene, this matrix is prepared by co-polymerization of chloromethylstyrene, styrene and divinylbenzene. Since the amount of chloromethylstyrene added to the polymerization reaction can be precisely controlled, this leads to a highly defined resin with little batch to batch variation in functionality. The swelling characteristics of such resins are also more reproducible since the process of manufacture does not introduce additional cross-linking, as is the case with resins produced by chloromethylation. For applications of REM resin in SPOS see references [2-4].

Literature references

[1] A. Brown, et al. (1997) J. Am. Chem. Soc., 119, 3288.
[2] J. Cottney, et al. (1999) Bioorg. Med. Chem. Lett., 9, 1323.
[3] A. Born, et al. (2001) Bioorg. Med. Chem. Lett., 11, 2351.
[4] S. Caix-Haumesser, et al. (2001) Tetrahedron Lett., 42, 3721.

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of chlorine after derivatization with 4-chloro-benzylamine): 0.80 - 1.20 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene-1 % DVB), 50 - 100 mesh.

Other Notes

Replaces: 01-64-0393

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
855115855130855045
description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis, reactivity: amine reactive

reaction suitability

reaction type: Boc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

Quality Level

200

Quality Level

200

Quality Level

400

Quality Level

400

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

form

beads

form

beads

form

powder

form

beads


Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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